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A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule
A number of autoimmune diseases are associated with the genotypes of human leukocyte antigen class II (HLA), some of which present peptides derived from self-proteins, resulting in clonal expansion of self-reactive T cells. Therefore, selective inhibition of self-peptide loading onto such disease-as...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533769/ https://www.ncbi.nlm.nih.gov/pubmed/28754892 http://dx.doi.org/10.1038/s41598-017-07080-4 |