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Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis

EZH2, a subunit of the polycomb repressive complex 2 (PRC2) catalyzing trimethylation of histone H3 lysine 27 (H3K27), induces epithelial-mesenchymal transition (EMT) in cancers. However, whether EZH2 regulates EMT in endometriosis is unclear. Here, we show that EZH2 expression, along with its assoc...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Dong, Peixin, Liu, Xishi, Sakuragi, Noriaki, Guo, Sun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533797/
https://www.ncbi.nlm.nih.gov/pubmed/28754964
http://dx.doi.org/10.1038/s41598-017-06920-7

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