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Recent advances in epilepsy

This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs...

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Detalles Bibliográficos
Autor principal: Manford, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533817/
https://www.ncbi.nlm.nih.gov/pubmed/28120042
http://dx.doi.org/10.1007/s00415-017-8394-2
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author Manford, Mark
author_facet Manford, Mark
author_sort Manford, Mark
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description This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy’s broader comorbidity, especially depression.
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spelling pubmed-55338172017-08-11 Recent advances in epilepsy Manford, Mark J Neurol Neurological Update This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy’s broader comorbidity, especially depression. Springer Berlin Heidelberg 2017-01-24 2017 /pmc/articles/PMC5533817/ /pubmed/28120042 http://dx.doi.org/10.1007/s00415-017-8394-2 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Neurological Update
Manford, Mark
Recent advances in epilepsy
title Recent advances in epilepsy
title_full Recent advances in epilepsy
title_fullStr Recent advances in epilepsy
title_full_unstemmed Recent advances in epilepsy
title_short Recent advances in epilepsy
title_sort recent advances in epilepsy
topic Neurological Update
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533817/
https://www.ncbi.nlm.nih.gov/pubmed/28120042
http://dx.doi.org/10.1007/s00415-017-8394-2
work_keys_str_mv AT manfordmark recentadvancesinepilepsy