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Recent advances in epilepsy
This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533817/ https://www.ncbi.nlm.nih.gov/pubmed/28120042 http://dx.doi.org/10.1007/s00415-017-8394-2 |
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author | Manford, Mark |
author_facet | Manford, Mark |
author_sort | Manford, Mark |
collection | PubMed |
description | This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy’s broader comorbidity, especially depression. |
format | Online Article Text |
id | pubmed-5533817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-55338172017-08-11 Recent advances in epilepsy Manford, Mark J Neurol Neurological Update This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy’s broader comorbidity, especially depression. Springer Berlin Heidelberg 2017-01-24 2017 /pmc/articles/PMC5533817/ /pubmed/28120042 http://dx.doi.org/10.1007/s00415-017-8394-2 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Neurological Update Manford, Mark Recent advances in epilepsy |
title | Recent advances in epilepsy |
title_full | Recent advances in epilepsy |
title_fullStr | Recent advances in epilepsy |
title_full_unstemmed | Recent advances in epilepsy |
title_short | Recent advances in epilepsy |
title_sort | recent advances in epilepsy |
topic | Neurological Update |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533817/ https://www.ncbi.nlm.nih.gov/pubmed/28120042 http://dx.doi.org/10.1007/s00415-017-8394-2 |
work_keys_str_mv | AT manfordmark recentadvancesinepilepsy |