(47)Sc production development by cyclotron irradiation of (48)Ca

The therapeutic radionuclide (47)Sc was produced through the (48)Ca(p,2n) channel on a proton beam accelerator. The obtained results show that the optimum proton energies are in the range of 24–17 MeV, giving the possibility to produce (47)Sc radionuclide containing 7.4% of (48)Sc. After activation,...

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Detalles Bibliográficos
Autores principales: Misiak, R., Walczak, R., Wąs, B., Bartyzel, M., Mietelski, J. W., Bilewicz, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533854/
https://www.ncbi.nlm.nih.gov/pubmed/28804186
http://dx.doi.org/10.1007/s10967-017-5321-z
Descripción
Sumario:The therapeutic radionuclide (47)Sc was produced through the (48)Ca(p,2n) channel on a proton beam accelerator. The obtained results show that the optimum proton energies are in the range of 24–17 MeV, giving the possibility to produce (47)Sc radionuclide containing 7.4% of (48)Sc. After activation, the powdery CaCO(3) target material was dissolved in HCl and scandium isotopes were isolated from the targets. The performed separation experiments indicate that, due to the simplicity of the operations and the chemical purity of the obtained (47)Sc the best separation process is when scandium radioisotopes are separated on the 0.2 µm filter.

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