Familial Alzheimer’s Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants

Familial (FAD) and sporadic (SAD) Alzheimer’s disease do not share all pathomechanisms, but knowledge on their molecular differences is limited. We previously reported that cell cycle control distinguishes lymphocytes from SAD and FAD patients. Significant differences were found in p21 levels of SAD...

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Detalles Bibliográficos
Autores principales: Wojsiat, Joanna, Laskowska-Kaszub, Katarzyna, Alquézar, Carolina, Białopiotrowicz, Emilia, Esteras, Noemi, Zdioruk, Mykola, Martin-Requero, Angeles, Wojda, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533859/
https://www.ncbi.nlm.nih.gov/pubmed/27644130
http://dx.doi.org/10.1007/s12035-016-0105-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533859/
https://www.ncbi.nlm.nih.gov/pubmed/27644130
http://dx.doi.org/10.1007/s12035-016-0105-y

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