Cargando…

Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control

Intact and broad immune cell effector functions and specific individual cytokines have been linked to HIV disease outcome, but their relative contribution to HIV control remains unclear. We asked whether the proteome of secreted cytokines and signaling factors in peripheral blood can be used to disc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruiz-Riol, M., Berdnik, D., Llano, A., Mothe, B., Gálvez, C., Pérez-Álvarez, S., Oriol-Tordera, B., Olvera, A., Silva-Arrieta, S., Meulbroek, M., Pujol, F., Coll, J., Martinez-Picado, J., Ganoza, C., Sanchez, J., Gómez, G., Wyss-Coray, T., Brander, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533920/ https://www.ncbi.nlm.nih.gov/pubmed/28592538 http://dx.doi.org/10.1128/JVI.00441-17

Ejemplares similares

Mechanisms of Abrupt Loss of Virus Control in a Cohort of Previous HIV Controllers
por: Rosás-Umbert, Miriam, et al.
Publicado: (2019)

Interleukin-27 Promotes Divergent Effects on HIV-1 Infection in Peripheral Blood Mononuclear Cells through BST-2/Tetherin
por: Temerozo, Jairo R., et al.
Publicado: (2023)

Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection
por: Harker, James A., et al.
Publicado: (2018)

Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages
por: Wang, Zhao-Yang, et al.
Publicado: (2020)

Control of HIV-1 Pathogenesis in Viremic Nonprogressors Is Independent of Gag-Specific Cytotoxic T Lymphocyte Responses
por: Salgado, Maria, et al.
Publicado: (2018)

Viral and Cellular Factors Leading to the Loss of CD4 Homeostasis in HIV-1 Viremic Nonprogressors
por: Colomer-Lluch, Marta, et al.
Publicado: (2022)

Associations of IL-27 Polymorphisms and Serum IL-27p28 Levels With Osteosarcoma Risk
por: Tang, Yu-jin, et al.
Publicado: (2014)

Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus
por: Busse, D. C., et al.
Publicado: (2020)

Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18
por: Chen, Kevin C., et al.
Publicado: (2016)

Defensive Perimeter in the Central Nervous System: Predominance of Astrocytes and Astrogliosis during Recovery from Varicella-Zoster Virus Encephalitis
por: Carpenter, John E., et al.
Publicado: (2015)

Limiting viral replication in hepatocytes alters Rift Valley fever virus disease manifestations
por: Xu, Lingqing, et al.
Publicado: (2023)

Role of African Swine Fever Virus Proteins EP153R and EP402R in Reducing Viral Persistence in Blood and Virulence in Pigs Infected with BeninΔDP148R
por: Petrovan, Vlad, et al.
Publicado: (2022)

Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge
por: Reis, Ana L., et al.
Publicado: (2017)

Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection
por: Scharf, Lydia, et al.
Publicado: (2020)

An Alphaherpesvirus Exploits Antimicrobial β-Defensins To Initiate Respiratory Tract Infection
por: Van Cleemput, Jolien, et al.
Publicado: (2020)

Pharmacological Modulation of the Wnt/β-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4(+) T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques
por: Mavigner, M., et al.
Publicado: (2019)

Differential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection
por: Rathakrishnan, Anusyah, et al.
Publicado: (2022)

Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research
por: Holguin, Leo, et al.
Publicado: (2022)

SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway
por: Chen, Da-Yuan, et al.
Publicado: (2021)

Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses
por: Deng, Xufang, et al.
Publicado: (2019)

Zika Virus Infection of Pregnant Ifnar1(−/−) Mice Triggers Strain-Specific Differences in Fetal Outcomes
por: Bohm, Ellie K., et al.
Publicado: (2021)

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Primary African Isolates
por: Lorenzi, Julio C. C., et al.
Publicado: (2021)

Modified Vaccinia Virus Ankara Can Induce Optimal CD8(+) T Cell Responses to Directly Primed Antigens Depending on Vaccine Design
por: Wong, Yik Chun, et al.
Publicado: (2019)

HIV-Infected Macrophages Are Infected and Killed by the Interferon-Sensitive Rhabdovirus MG1
por: Sandstrom, Teslin S., et al.
Publicado: (2021)

Editorial: IL-27 in health and disease
por: Imamichi, Tomozumi, et al.
Publicado: (2023)

Proteomic and Functional Analyses of the Virion Transmembrane Proteome of Cyprinid Herpesvirus 3
por: Vancsok, Catherine, et al.
Publicado: (2017)

Inefficient HIV-1 trans Infection of CD4(+) T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN
por: DeLucia, Diana C., et al.
Publicado: (2018)

Direct Priming of CD8(+) T Cells Persists in the Face of Cowpox Virus Inhibitors of Antigen Presentation
por: Lin, Leon C. W., et al.
Publicado: (2021)

Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus
por: Deng, Xufang, et al.
Publicado: (2020)

In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells
por: Laksono, Brigitta M., et al.
Publicado: (2018)

Time Series Transcriptomic Analysis of Bronchoalveolar Lavage Cells from Piglets Infected with Virulent or Low-Virulent Porcine Reproductive and Respiratory Syndrome Virus 1
por: Sánchez-Carvajal, J. M., et al.
Publicado: (2022)

Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques
por: Hsu, Denise C., et al.
Publicado: (2018)

A Highly Unusual V1 Region of Env in an Elite Controller of HIV Infection
por: Silver, Zachary A., et al.
Publicado: (2019)

Acute-Phase CD8 T Cell Responses That Select for Escape Variants Are Needed to Control Live Attenuated Simian Immunodeficiency Virus
por: Harris, Max, et al.
Publicado: (2013)

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA
por: Gaebler, Christian, et al.
Publicado: (2021)

HLA-B*14:02-Restricted Env-Specific CD8(+) T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection
por: Leitman, Ellen M., et al.
Publicado: (2017)

Herpes Simplex Virus 1 Induces Brain Inflammation and Multifocal Demyelination in the Cotton Rat Sigmodon hispidus
por: Boukhvalova, Marina S., et al.
Publicado: (2019)

High Production Rates Sustain In Vivo Levels of PD-1(high) Simian Immunodeficiency Virus-Specific CD8 T Cells in the Face of Rapid Clearance
por: Petrovas, Constantinos, et al.
Publicado: (2013)

Delayed Sequelae of Neonatal Respiratory Syncytial Virus Infection Are Dependent on Cells of the Innate Immune System
por: Harker, James A., et al.
Publicado: (2014)

Deep Gene Sequence Cluster Analyses of Multi-Virus-Infected Mucosal Tissue Reveal Enhanced Transmission of Acute HIV-1
por: Klein, Katja, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0fbhkc7l2uiovgu4hffgnjv6pd