Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway

Hyperglycemia is a common feature of diabetes mellitus, considered as a risk factor for cancer. However, its direct effects in cancer cell behavior are relatively unexplored. Herein we show that high glucose concentration induces aberrant glycosylation, increased cell proliferation, invasion and tum...

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Detalles Bibliográficos
Autores principales: Vasconcelos-dos-Santos, A, Loponte, H F B R, Mantuano, N R, Oliveira, I A, de Paula, I F, Teixeira, L K, de-Freitas-Junior, J C M, Gondim, K C, Heise, N, Mohana-Borges, R, Morgado-Díaz, J A, Dias, W B, Todeschini, A R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533945/
https://www.ncbi.nlm.nih.gov/pubmed/28319096
http://dx.doi.org/10.1038/oncsis.2017.2

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