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RCN1 suppresses ER stress-induced apoptosis via calcium homeostasis and PERK–CHOP signaling
Endoplasmic reticulum (ER) stress is caused by the disturbance of ER homeostasis and leads to the activation of the unfolded protein response (UPR), which alleviates stress at an early stage and triggers apoptosis if homeostasis fails over a prolonged timeframe. Here, we report that reticulocalbin 1...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533947/ https://www.ncbi.nlm.nih.gov/pubmed/28319095 http://dx.doi.org/10.1038/oncsis.2017.6 |