Cargando…

Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment

BACKGROUND: Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevelopmental outcomes are more frequent and/or more severe when toxic exposures int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhaoxi, Henn, Birgit Claus, Wang, Chaolong, Wei, Yongyue, Su, Li, Sun, Ryan, Chen, Han, Wagner, Peter J., Lu, Quan, Lin, Xihong, Wright, Robert, Bellinger, David, Kile, Molly, Mazumdar, Maitreyi, Tellez-Rojo, Martha Maria, Schnaas, Lourdes, Christiani, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534076/ https://www.ncbi.nlm.nih.gov/pubmed/28754176 http://dx.doi.org/10.1186/s12940-017-0288-3

Ejemplares similares

Identification of Novel Loci Associated with Infant Cognitive Ability
por: Sun, Ryan, et al.
Publicado: (2018)

Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment
por: Henn, Birgit Claus, et al.
Publicado: (2011)

Modification of the effects of prenatal manganese exposure on child neurodevelopment by maternal anemia and iron deficiency
por: Kupsco, Allison, et al.
Publicado: (2020)

Maternal and Cord Blood Manganese Concentrations and Early Childhood Neurodevelopment among Residents near a Mining-Impacted Superfund Site
por: Claus Henn, Birgit, et al.
Publicado: (2017)

The Joint Effect of Prenatal Exposure to Metal Mixtures on Neurodevelopmental Outcomes at 20–40 Months of Age: Evidence from Rural Bangladesh
por: Valeri, Linda, et al.
Publicado: (2017)

Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models
por: Claus Henn, Birgit, et al.
Publicado: (2011)

Neurodevelopmental outcomes among 2- to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water
por: Rodrigues, Ema G., et al.
Publicado: (2016)

Household use of crop residues and fuelwood for cooking and newborn birth size in rural Bangladesh
por: Lee, Mi-Sun, et al.
Publicado: (2022)

Umbilical Cord Blood Metal Mixtures and Birth Size in Bangladeshi Children
por: Lee, Mi-Sun, et al.
Publicado: (2021)

Calculation of Mercury’s Effects on Neurodevelopment: Bellinger Responds
por: Bellinger, David C.
Publicado: (2012)

Infant Mental Development Index: Hu et al. Respond
por: Hu, Howard, et al.
Publicado: (2007)

Fetal Lead Exposure at Each Stage of Pregnancy as a Predictor of Infant Mental Development
por: Hu, Howard, et al.
Publicado: (2006)

Time-varying associations between prenatal metal mixtures and rapid visual processing in children
por: Levin-Schwartz, Yuri, et al.
Publicado: (2019)

Prenatal Exposures to Environmental Chemicals and Children's Neurodevelopment: An Update
por: Bellinger, David C
Publicado: (2013)

Estimating Effects of Arsenic Exposure During Pregnancy on Perinatal Outcomes in a Bangladeshi Cohort
por: Kile, Molly L., et al.
Publicado: (2016)

A prospective cohort study of the association between drinking water arsenic exposure and self-reported maternal health symptoms during pregnancy in Bangladesh
por: Kile, Molly L, et al.
Publicado: (2014)

Neurotoxic Metal Coexposures: Claus Henn et al. Respond
por: Henn, Birgit Claus, et al.
Publicado: (2012)

Prenatal Co-Exposure to Manganese, Mercury, and Lead, and Neurodevelopment in Children during the First Year of Life
por: Farías, Paulina, et al.
Publicado: (2022)

In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children
por: Wagner, Peter J., et al.
Publicado: (2016)

The UNC-Wisconsin Rhesus Macaque Neurodevelopment Database: A Structural MRI and DTI Database of Early Postnatal Development
por: Young, Jeffrey T., et al.
Publicado: (2017)

A Strategy for Comparing the Contributions of Environmental Chemicals and Other Risk Factors to Neurodevelopment of Children
por: Bellinger, David C.
Publicado: (2011)

Global Metabolomic Profiling Reveals an Association of Metal Fume Exposure and Plasma Unsaturated Fatty Acids
por: Wei, Yongyue, et al.
Publicado: (2013)

Prenatal Arsenic Exposure and Birth Outcomes among a Population Residing near a Mining-Related Superfund Site
por: Henn, Birgit Claus, et al.
Publicado: (2016)

Prenatal Lead Levels, Plasma Amyloid β Levels, and Gene Expression in Young Adulthood
por: Mazumdar, Maitreyi, et al.
Publicado: (2012)

Contaminated Turmeric Is a Potential Source of Lead Exposure for Children in Rural Bangladesh
por: Gleason, Kelsey, et al.
Publicado: (2014)

Of decrements and disorders: assessing impairments in neurodevelopment in prospective studies of environmental toxicant exposures
por: Sagiv, Sharon K, et al.
Publicado: (2015)

Correlation of Global and Gene-Specific DNA Methylation in Maternal-Infant Pairs
por: Kile, Molly L., et al.
Publicado: (2010)

Toddler temperament and prenatal exposure to lead and maternal depression
por: Stroustrup, Annemarie, et al.
Publicado: (2016)

Lead in Air in Bangladesh: Exposure in a Rural Community with Elevated Blood Lead Concentrations among Young Children
por: Woo, May K., et al.
Publicado: (2018)

The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP
por: Norris, Adam D., et al.
Publicado: (2014)

Gene-environment interaction effects on lung function- a genome-wide association study within the Framingham heart study
por: Liao, Shu-Yi, et al.
Publicado: (2013)

UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways
por: MacNeil, Lesley T., et al.
Publicado: (2009)

Prenatal p,p´-DDE Exposure and Neurodevelopment among Children 3.5–5 Years of Age
por: Torres-Sánchez, Luisa, et al.
Publicado: (2012)

Differential association of lead on length by zinc status in two-year old Mexican children
por: Cantoral, Alejandra, et al.
Publicado: (2015)

Antinuclear antibody prevalence in a general pediatric cohort from Mexico City: discordance between immunofluorescence and multiplex assays
por: Somers, Emily C, et al.
Publicado: (2016)

In Utero p,p′-DDE Exposure and Infant Neurodevelopment: A Perinatal Cohort in Mexico
por: Torres-Sánchez, Luisa, et al.
Publicado: (2007)

Variants in Iron Metabolism Genes Predict Higher Blood Lead Levels in Young Children
por: Hopkins, Marianne R., et al.
Publicado: (2008)

Plasma Neutrophil Elastase and Elafin Imbalance Is Associated with Acute Respiratory Distress Syndrome (ARDS) Development
por: Wang, Zhaoxi, et al.
Publicado: (2009)

Design and analysis issues in gene and environment studies
por: Liu, Chen-yu, et al.
Publicado: (2012)

Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study
por: Mérida-Ortega, Ángel, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_g75a70gu69flqtphmrb9ksfdqd