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In vivo plug-and-play: a modular multi-enzyme single-cell catalyst for the asymmetric amination of ketoacids and ketones
BACKGROUND: Transaminases have become a key tool in biocatalysis to introduce the amine functionality into a range of molecules like prochiral α-ketoacids and ketones. However, due to the necessity of shifting the equilibrium towards the product side (depending on the amine donor) an efficient amina...
Autores principales: | Farnberger, Judith E., Lorenz, Elisabeth, Richter, Nina, Wendisch, Volker F., Kroutil, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534079/ https://www.ncbi.nlm.nih.gov/pubmed/28754115 http://dx.doi.org/10.1186/s12934-017-0750-5 |
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