Antivirals for allosteric inhibition of Zika virus using a homology model and experimentally determined structure of envelope protein

OBJECTIVE: An approach to inhibiting enveloped flaviviruses is to deter the ability of the envelope protein(s) binding onto glycoproteins. In previous work, using a small ~100-amino acid homology model of Zika virus envelope protein (ZVEP), we proved the susceptibility of Zika virus to inhibition. I...

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Detalles Bibliográficos
Autores principales: Fernando, Sandun, Fernando, Teshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534091/
https://www.ncbi.nlm.nih.gov/pubmed/28754167
http://dx.doi.org/10.1186/s13104-017-2685-7

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