Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration

BACKGROUND: Insertion of retroviral genome DNA occurs in the chromatin of the host cell. This step is modulated by chromatin structure as nucleosomes compaction was shown to prevent HIV-1 integration and chromatin remodeling has been reported to affect integration efficiency. LEDGF/p75-mediated targ...

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Detalles Bibliográficos
Autores principales: Matysiak, Julien, Lesbats, Paul, Mauro, Eric, Lapaillerie, Delphine, Dupuy, Jean-William, Lopez, Angelica P., Benleulmi, Mohamed Salah, Calmels, Christina, Andreola, Marie-Line, Ruff, Marc, Llano, Manuel, Delelis, Olivier, Lavigne, Marc, Parissi, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534098/
https://www.ncbi.nlm.nih.gov/pubmed/28754126
http://dx.doi.org/10.1186/s12977-017-0363-4

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