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Identifying genomic targets for protein over-expression by “omics” analysis of Quiescent Escherichia coli cultures

BACKGROUND: A cellular stress response is triggered upon induction of recombinant protein expression which feedback inhibits both growth as well as protein synthesis. In order to separate these two effects, it was decided to study “quiescent cultures” which continue to be metabolically active and ex...

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Detalles Bibliográficos
Autores principales: Mahalik, Shubhashree, Sharma, Ashish Kumar, Jain, Priyanka, Mukherjee, Krishna Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534100/
https://www.ncbi.nlm.nih.gov/pubmed/28754100
http://dx.doi.org/10.1186/s12934-017-0744-3

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