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Identifying genomic targets for protein over-expression by “omics” analysis of Quiescent Escherichia coli cultures
BACKGROUND: A cellular stress response is triggered upon induction of recombinant protein expression which feedback inhibits both growth as well as protein synthesis. In order to separate these two effects, it was decided to study “quiescent cultures” which continue to be metabolically active and ex...
Autores principales: | Mahalik, Shubhashree, Sharma, Ashish Kumar, Jain, Priyanka, Mukherjee, Krishna Jyoti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534100/ https://www.ncbi.nlm.nih.gov/pubmed/28754100 http://dx.doi.org/10.1186/s12934-017-0744-3 |
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