Long-term spironolactone treatment reduces coronary TRPC expression, vasoconstriction, and atherosclerosis in metabolic syndrome pigs

Coronary transient receptor potential canonical (TRPC) channel expression is elevated in metabolic syndrome (MetS). However, differential contribution of TRPCs to coronary pathology in MetS is not fully elucidated. We investigated the roles of TRPC1 and TRPC6 isoforms in coronary arteries of MetS pi...

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Detalles Bibliográficos
Autores principales: Li, Wennan, Chen, Xingjuan, Riley, Ashley M., Hiett, S. Christopher, Temm, Constance J., Beli, Eleni, Long, Xin, Chakraborty, Saikat, Alloosh, Mouhamad, White, Fletcher A., Grant, Maria B., Sturek, Michael, Obukhov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534204/
https://www.ncbi.nlm.nih.gov/pubmed/28756533
http://dx.doi.org/10.1007/s00395-017-0643-0

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