Recovery following Thyroxine Treatment Withdrawal, but Not Propylthiouracil, Averts In Vivo and Ex Vivo Thyroxine-Provoked Cardiac Complications in Adult FVB/N Mice

Persistent cardiovascular pathology has been described in hyperthyroid patients even with effective antithyroid treatment. Here, we studied the effect of a well-known antithyroid drug, propylthiouracil (PTU; 20 mg/kg/day), on thyroxine (T4; 500 µg/kg/day)-induced increase in blood pressure (BP), car...

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Detalles Bibliográficos
Autores principales: Saad, Nancy S., Repas, Steven J., Floyd, Kyle, Janssen, Paul M. L., Elnakish, Mohammad T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534272/
https://www.ncbi.nlm.nih.gov/pubmed/28791308
http://dx.doi.org/10.1155/2017/6071031

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