Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells

Previously, we reported that treatment with the G9a histone methyltransferase inhibitor BIX01294 causes bone marrow mesenchymal stem cells (MSCs) to exhibit a cardiocompetent phenotype, as indicated by the induction of the precardiac markers Mesp1 and brachyury. Here, we report that combining the hi...

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Detalles Bibliográficos
Autores principales: Yang, Jinpu, Kaur, Keerat, Edwards, John G., Eisenberg, Carol A., Eisenberg, Leonard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534312/
https://www.ncbi.nlm.nih.gov/pubmed/28791052
http://dx.doi.org/10.1155/2017/3464953

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