RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network

The retinoic acid receptor-related orphan receptor-α (RORα) is an important regulator of various biological processes, including cerebellum development, circadian rhythm and cancer. Here, we show that hepatic RORα controls lipid homeostasis by negatively regulating transcriptional activity of peroxi...

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Detalles Bibliográficos
Autores principales: Kim, Kyeongkyu, Boo, Kyungjin, Yu, Young Suk, Oh, Se Kyu, Kim, Hyunkyung, Jeon, Yoon, Bhin, Jinhyuk, Hwang, Daehee, Kim, Keun Il, Lee, Jun-Su, Im, Seung-Soon, Yoon, Seul Gi, Kim, Il Yong, Seong, Je Kyung, Lee, Ho, Fang, Sungsoon, Baek, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534431/
https://www.ncbi.nlm.nih.gov/pubmed/28757615
http://dx.doi.org/10.1038/s41467-017-00215-1

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