Cargando…

Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus

BACKGROUND: Hofbauer cells (HBCs) are macrophages of the feto-placental unit. Despite the general view that these cells have an anti-inflammatory M2 phenotype, recent studies have claimed that pregnancy pathologies—e.g., gestational diabetes mellitus (GDM)—cause a switch from an M2 to an M1 pro-infl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schliefsteiner, Carolin, Peinhaupt, Miriam, Kopp, Susanne, Lögl, Jelena, Lang-Olip, Ingrid, Hiden, Ursula, Heinemann, Akos, Desoye, Gernot, Wadsack, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534476/ https://www.ncbi.nlm.nih.gov/pubmed/28824621 http://dx.doi.org/10.3389/fimmu.2017.00888

Ejemplares similares

Placental Hofbauer Cell Polarization Resists Inflammatory Cues In Vitro
por: Schliefsteiner, Carolin, et al.
Publicado: (2020)

Dysregulation of Placental Endothelial Lipase in Obese Women With Gestational Diabetes Mellitus
por: Gauster, Martin, et al.
Publicado: (2011)

Maternal Gestational Diabetes Mellitus increases placental and foetal lipoprotein-associated Phospholipase A2 which might exert protective functions against oxidative stress
por: Schliefsteiner, Carolin, et al.
Publicado: (2017)

The Distinct Role of the HDL Receptor SR-BI in Cholesterol Homeostasis of Human Placental Arterial and Venous Endothelial Cells
por: Strahlhofer-Augsten, Manuela, et al.
Publicado: (2022)

Glucose, Insulin, and Oxygen Interplay in Placental Hypervascularisation in Diabetes Mellitus
por: Cvitic, Silvija, et al.
Publicado: (2014)

Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia
por: Mercnik, Monika Horvat, et al.
Publicado: (2023)

Human Milk Oligosaccharides in Cord Blood Are Altered in Gestational Diabetes and Stimulate Feto-Placental Angiogenesis In Vitro
por: Hoch, Denise, et al.
Publicado: (2021)

The Human Placental Sexome Differs between Trophoblast Epithelium and Villous Vessel Endothelium
por: Cvitic, Silvija, et al.
Publicado: (2013)

Pigment epithelium-derived factor (PEDF): a novel trophoblast-derived factor limiting feto-placental angiogenesis in late pregnancy
por: Loegl, Jelena, et al.
Publicado: (2016)

Phenotypic and functional characterization of first-trimester human placental macrophages, Hofbauer cells
por: Thomas, Jake R., et al.
Publicado: (2020)

Examining the Effects of Gestational Physical Activity and Hofbauer Cell Polarization on Angiogenic Factors
por: Goudreau, Alexandra D., et al.
Publicado: (2023)

Placental mobilization of free fatty acids contributes to altered materno-fetal transfer in obesity
por: Hirschmugl, Birgit, et al.
Publicado: (2021)

Placental Macrophage (Hofbauer Cell) Responses to Infection During Pregnancy: A Systematic Scoping Review
por: Fakonti, Georgia, et al.
Publicado: (2022)

Differential Activation of Fetal Hofbauer Cells in Primigravidas Is Associated with Decreased Birth Weight in Symptomatic Placental Malaria
por: Gaw, Stephanie L., et al.
Publicado: (2019)

Placental Hofbauer cells assemble and sequester HIV-1 in tetraspanin-positive compartments that are accessible to broadly neutralizing antibodies
por: Johnson, Erica L, et al.
Publicado: (2015)

Hofbauer Cells: Their Role in Healthy and Complicated Pregnancy
por: Reyes, Leticia, et al.
Publicado: (2018)

Placental Hofbauer cells assemble and sequester HIV-1 in tetraspanin and DC SIGN positive compartments that are accessible to neutralizing antibodies
por: Johnson, Erica L, et al.
Publicado: (2014)

Comparative Analysis of Immunohistochemical Staining Intensity Determined by Light Microscopy, ImageJ and QuPath in Placental Hofbauer Cells
por: Cizkova, Katerina, et al.
Publicado: (2021)

Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus
por: Blazevic, Sofia, et al.
Publicado: (2017)

Gestational Hypertension and High-Density Lipoprotein Function: An Explorative Study in Overweight/Obese Women of the DALI Cohort
por: Stadler, Julia T., et al.
Publicado: (2022)

Gestational age-dependent decrease in fetal Hofbauer cells in placentas from pregnancies exposed to wildfire smoke in California
por: Basilio, Emilia, et al.
Publicado: (2023)

Pregnancies in Diabetes and Obesity: The Capacity-Load Model of Placental Adaptation
por: Desoye, Gernot, et al.
Publicado: (2021)

Placental Hofbauer cells limit HIV-1 replication and potentially offset mother to child transmission (MTCT) by induction of immunoregulatory cytokines
por: Johnson, Erica L, et al.
Publicado: (2012)

Viral infection, proliferation, and hyperplasia of Hofbauer cells and absence of inflammation characterize the placental pathology of fetuses with congenital Zika virus infection
por: Schwartz, David A.
Publicado: (2017)

Prostaglandins and Their Receptors in Eosinophil Function and As Therapeutic Targets
por: Peinhaupt, Miriam, et al.
Publicado: (2017)

Variable promoter methylation contributes to differential expression of key genes in human placenta-derived venous and arterial endothelial cells
por: Joo, Jihoon E, et al.
Publicado: (2013)

Maternal obesity modulates intracellular lipid turnover in the human term placenta
por: Hirschmugl, B, et al.
Publicado: (2017)

Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors
por: Azari, Siavash, et al.
Publicado: (2021)

Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner
por: Prokesch, Andreas, et al.
Publicado: (2017)

Respiratory syncytial virus exhibits differential tropism for distinct human placental cell types with Hofbauer cells acting as a permissive reservoir for infection
por: Bokun, Vladimir, et al.
Publicado: (2019)

The first trimester human trophoblast cell line ACH-3P: A novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations – TNF-α stimulates MMP15 expression
por: Hiden, Ursula, et al.
Publicado: (2007)

Erythro-myeloid progenitor origin of Hofbauer cells in the early mouse placenta
por: Freyer, Laina, et al.
Publicado: (2022)

Human fetoplacental arterial and venous endothelial cells are differentially programmed by gestational diabetes mellitus, resulting in cell-specific barrier function changes
por: Cvitic, Silvija, et al.
Publicado: (2018)

Expression of matrix metalloproteinase 12 is highly specific for non-proliferating invasive trophoblasts in the first trimester and temporally regulated by oxygen-dependent mechanisms including HIF-1A
por: Hiden, Ursula, et al.
Publicado: (2017)

Transient Hyperglycemia and Hypoxia Induce Memory Effects in AngiomiR Expression Profiles of Feto-Placental Endothelial Cells
por: Strutz, Jasmin, et al.
Publicado: (2021)

Hofbauer cell function in the term placenta associates with adult cardiovascular and depressive outcomes
por: Fitzgerald, Eamon, et al.
Publicado: (2023)

Abnormal composition and function of high‐density lipoproteins in atopic dermatitis patients
por: Trieb, Markus, et al.
Publicado: (2018)

Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells
por: Riederer, Monika, et al.
Publicado: (2011)

Downregulation of p53 drives autophagy during human trophoblast differentiation
por: Gauster, Martin, et al.
Publicado: (2017)

Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps
por: Hjort, Line, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mvn9gac6pujdl7jhak98pbusbc