Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of developing psychiatric pathologies in later life. This link may be bridged by a defective microglial phenotype in the offspring induced by MIA, as microglia have key roles in the development and maintenance of...

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Detalles Bibliográficos
Autores principales: Mattei, D, Ivanov, A, Ferrai, C, Jordan, P, Guneykaya, D, Buonfiglioli, A, Schaafsma, W, Przanowski, P, Deuther-Conrad, W, Brust, P, Hesse, S, Patt, M, Sabri, O, Ross, T L, Eggen, B J L, Boddeke, E W G M, Kaminska, B, Beule, D, Pombo, A, Kettenmann, H, Wolf, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534948/
https://www.ncbi.nlm.nih.gov/pubmed/28485733
http://dx.doi.org/10.1038/tp.2017.80

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