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Gene-body 5-hydroxymethylation is associated with gene expression changes in the prefrontal cortex of depressed individuals
5-Hydroxymethylcytosine (5hmC) is a recently characterized epigenetic mark that is particularly abundant in brain tissue and that regulates gene transcription. We have recently begun to understand the important role of 5hmC in brain development, plasticity and disease, but there are currently little...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534961/ https://www.ncbi.nlm.nih.gov/pubmed/28485726 http://dx.doi.org/10.1038/tp.2017.93 |