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Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, ca...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535045/ https://www.ncbi.nlm.nih.gov/pubmed/28729377 http://dx.doi.org/10.1136/bcr-2017-220368 |
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author | Booth, Adam L Li, Christine Q Al-Dossari, Ghannam Ayed Stevenson, Heather L |
author_facet | Booth, Adam L Li, Christine Q Al-Dossari, Ghannam Ayed Stevenson, Heather L |
author_sort | Booth, Adam L |
collection | PubMed |
description | Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, calcified aortic valves are characterised by large, nodular masses within the aortic cusps. We report a case of dystrophic calcifications on a stenotic aortic valve encountered intraoperatively, which was suggestive of infective endocarditis and abscess formation. Aortic valve leaflets and necrotic-appearing thymic lymph node tissue were submitted for histology and special stains. Cultures were negative and histology did not show evidence of infection. Tissue histology demonstrated extensive dystrophic calcifications, which were polarised to reveal abundant calcium oxalate crystals. The benign nature of this unique pathological finding ruled out any suspicion of infection, avoiding a prolonged course of intravenous antibiotics in this patient. |
format | Online Article Text |
id | pubmed-5535045 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-55350452017-08-07 Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement Booth, Adam L Li, Christine Q Al-Dossari, Ghannam Ayed Stevenson, Heather L BMJ Case Rep Article Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, calcified aortic valves are characterised by large, nodular masses within the aortic cusps. We report a case of dystrophic calcifications on a stenotic aortic valve encountered intraoperatively, which was suggestive of infective endocarditis and abscess formation. Aortic valve leaflets and necrotic-appearing thymic lymph node tissue were submitted for histology and special stains. Cultures were negative and histology did not show evidence of infection. Tissue histology demonstrated extensive dystrophic calcifications, which were polarised to reveal abundant calcium oxalate crystals. The benign nature of this unique pathological finding ruled out any suspicion of infection, avoiding a prolonged course of intravenous antibiotics in this patient. BMJ Publishing Group 2017-07-19 /pmc/articles/PMC5535045/ /pubmed/28729377 http://dx.doi.org/10.1136/bcr-2017-220368 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Article Booth, Adam L Li, Christine Q Al-Dossari, Ghannam Ayed Stevenson, Heather L Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
title | Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
title_full | Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
title_fullStr | Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
title_full_unstemmed | Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
title_short | Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
title_sort | abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535045/ https://www.ncbi.nlm.nih.gov/pubmed/28729377 http://dx.doi.org/10.1136/bcr-2017-220368 |
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