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Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement

Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, ca...

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Autores principales: Booth, Adam L, Li, Christine Q, Al-Dossari, Ghannam Ayed, Stevenson, Heather L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535045/
https://www.ncbi.nlm.nih.gov/pubmed/28729377
http://dx.doi.org/10.1136/bcr-2017-220368
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author Booth, Adam L
Li, Christine Q
Al-Dossari, Ghannam Ayed
Stevenson, Heather L
author_facet Booth, Adam L
Li, Christine Q
Al-Dossari, Ghannam Ayed
Stevenson, Heather L
author_sort Booth, Adam L
collection PubMed
description Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, calcified aortic valves are characterised by large, nodular masses within the aortic cusps. We report a case of dystrophic calcifications on a stenotic aortic valve encountered intraoperatively, which was suggestive of infective endocarditis and abscess formation. Aortic valve leaflets and necrotic-appearing thymic lymph node tissue were submitted for histology and special stains. Cultures were negative and histology did not show evidence of infection. Tissue histology demonstrated extensive dystrophic calcifications, which were polarised to reveal abundant calcium oxalate crystals. The benign nature of this unique pathological finding ruled out any suspicion of infection, avoiding a prolonged course of intravenous antibiotics in this patient.
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spelling pubmed-55350452017-08-07 Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement Booth, Adam L Li, Christine Q Al-Dossari, Ghannam Ayed Stevenson, Heather L BMJ Case Rep Article Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, calcified aortic valves are characterised by large, nodular masses within the aortic cusps. We report a case of dystrophic calcifications on a stenotic aortic valve encountered intraoperatively, which was suggestive of infective endocarditis and abscess formation. Aortic valve leaflets and necrotic-appearing thymic lymph node tissue were submitted for histology and special stains. Cultures were negative and histology did not show evidence of infection. Tissue histology demonstrated extensive dystrophic calcifications, which were polarised to reveal abundant calcium oxalate crystals. The benign nature of this unique pathological finding ruled out any suspicion of infection, avoiding a prolonged course of intravenous antibiotics in this patient. BMJ Publishing Group 2017-07-19 /pmc/articles/PMC5535045/ /pubmed/28729377 http://dx.doi.org/10.1136/bcr-2017-220368 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Article
Booth, Adam L
Li, Christine Q
Al-Dossari, Ghannam Ayed
Stevenson, Heather L
Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
title Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
title_full Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
title_fullStr Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
title_full_unstemmed Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
title_short Abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
title_sort abundant dystrophic calcifications mimicking aortic valve abscess in a patient undergoing elective aortic valve replacement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535045/
https://www.ncbi.nlm.nih.gov/pubmed/28729377
http://dx.doi.org/10.1136/bcr-2017-220368
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