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Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa

Staphylococcus aureus (S. aureus) produces many different exotoxins including the gamma-toxins, HlgAB and HlgCB. Gamma-toxins form pores in both leukocyte and erythrocyte membranes, resulting in cell lysis. The genes encoding gamma-toxins are present in most strains of S. aureus, and are commonly ex...

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Detalles Bibliográficos
Autores principales: Gillman, Aaron N., Breshears, Laura M., Kistler, Charles K., Finnegan, Patrick M., Torres, Victor J., Schlievert, Patrick M., Peterson, Marnie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535149/
https://www.ncbi.nlm.nih.gov/pubmed/28657583
http://dx.doi.org/10.3390/toxins9070202