Cargando…

Ouabain Protects Human Renal Cells against the Cytotoxic Effects of Shiga Toxin Type 2 and Subtilase Cytotoxin

Hemolytic uremic syndrome (HUS) is one of the most common causes of acute renal failure in children. The majority of cases are associated with Shiga toxin (Stx)-producing Escherichia coli (STEC). In Argentina, HUS is endemic and presents the highest incidence rate in the world. STEC strains expressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amaral, María M., Girard, Magalí C., Álvarez, Romina S., Paton, Adrienne W., Paton, James C., Repetto, Horacio A., Sacerdoti, Flavia, Ibarra, Cristina A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535173/ https://www.ncbi.nlm.nih.gov/pubmed/28718802 http://dx.doi.org/10.3390/toxins9070226

Ejemplares similares

Action of Shiga Toxin Type-2 and Subtilase Cytotoxin on Human Microvascular Endothelial Cells
por: Amaral, María M., et al.
Publicado: (2013)

Combined Action of Shiga Toxin Type 2 and Subtilase Cytotoxin in the Pathogenesis of Hemolytic Uremic Syndrome
por: Álvarez, Romina S., et al.
Publicado: (2021)

Comparative Characterization of Shiga Toxin Type 2 and Subtilase Cytotoxin Effects on Human Renal Epithelial and Endothelial Cells Grown in Monolayer and Bilayer Conditions
por: Álvarez, Romina S., et al.
Publicado: (2016)

Effects of Escherichia Coli Subtilase Cytotoxin and Shiga Toxin 2 on Primary Cultures of Human Renal Tubular Epithelial Cells
por: Márquez, Laura B., et al.
Publicado: (2014)

Crosstalk between Human Microvascular Endothelial Cells and Tubular Epithelial Cells Modulates Pro-Inflammatory Responses Induced by Shiga Toxin Type 2 and Subtilase Cytotoxin
por: Álvarez, Romina S., et al.
Publicado: (2019)

Escherichia coli Subtilase Cytotoxin
por: Paton, Adrienne W., et al.
Publicado: (2010)

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes
por: Hu, Chih-Chi Andrew, et al.
Publicado: (2009)

A New Family of Potent AB(5) Cytotoxins Produced by Shiga Toxigenic Escherichia coli
por: Paton, Adrienne W., et al.
Publicado: (2004)

Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection
por: Tsutsuki, Hiroyasu, et al.
Publicado: (2022)

Novel Aspects of the SubA Subunit of the Subtilase Cytotoxin
por: Sessler, Katharina, et al.
Publicado: (2022)

Molecular analysis of subtilase cytotoxin genes of food-borne Shiga toxin-producing Escherichia coli reveals a new allelic subAB variant
por: Funk, Joschua, et al.
Publicado: (2013)

Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival
por: Yahiro, Kinnosuke, et al.
Publicado: (2020)

Correction: Molecular analysis of subtilase cytotoxin genes of food-borne Shiga toxin-producing Escherichia coli reveals a new allelic subAB variant
por: Funk, Joschua, et al.
Publicado: (2014)

Draft Genome Sequences of Five Shiga Toxin-Producing Escherichia coli Isolates Harboring the New and Recently Described Subtilase Cytotoxin Allelic Variant subAB(2-3)
por: Tasara, Taurai, et al.
Publicado: (2017)

GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy
por: Firczuk, M, et al.
Publicado: (2013)

Variants of Escherichia coli Subtilase Cytotoxin Subunits Show Differences in Complex Formation In Vitro
por: Krause, Maike, et al.
Publicado: (2019)

Shiga Toxin-Producing Escherichia coli Infections during Pregnancy
por: Sacerdoti, Flavia, et al.
Publicado: (2018)

Human Recombinant Fab Fragment Neutralizes Shiga Toxin Type 2 Cytotoxic Effects in vitro and in vivo
por: Luz, Daniela, et al.
Publicado: (2018)

Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo
por: GABRYSIAK, MAGDALENA, et al.
Publicado: (2016)

Effects of Shiga Toxin Type 2 on Maternal and Fetal Status in Rats in the Early Stage of Pregnancy
por: Sacerdoti, Flavia, et al.
Publicado: (2014)

Shiga Toxin–producing Escherichia coli Strains Negative for Locus of Enterocyte Effacement
por: Newton, Hayley J., et al.
Publicado: (2009)

Therapeutic use of a receptor mimic probiotic reduces intestinal Shiga toxin levels in a piglet model of hemolytic uremic syndrome
por: Hostetter, Shannon J, et al.
Publicado: (2014)

Duplication and diversification of a unique chromosomal virulence island hosting the subtilase cytotoxin in Escherichia coli ST58
por: Wyrsch, Ethan R., et al.
Publicado: (2020)

Occurrence of subtilase cytotoxin and relation with other virulence factors in verocytotoxigenic Escherichia coli isolated from food and cattle in Argentina
por: Velandia, Claudia V. Granobles, et al.
Publicado: (2011)

A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor
por: Yamaji, Toshiyuki, et al.
Publicado: (2019)

Therapeutic Antibodies Against Shiga Toxins: Trends and Perspectives
por: Henrique, Izabella de Macedo, et al.
Publicado: (2022)

Human Glomerular Endothelial Cells Treated With Shiga Toxin Type 2 Activate γδ T Lymphocytes
por: Rosso, David Antonio, et al.
Publicado: (2021)

Contact with farming environment as a major risk factor for Shiga toxin (Vero cytotoxin)-producing Escherichia coli O157 infection in humans.
por: O'Brien, S J, et al.
Publicado: (2001)

Soluble CD40 Ligand and Oxidative Response Are Reciprocally Stimulated during Shiga Toxin-Associated Hemolytic Uremic Syndrome
por: Abrey Recalde, Maria J., et al.
Publicado: (2017)

Detection of Shiga Toxin-Producing Escherichia coli (STEC) in the Endocervix of Asymptomatic Pregnant Women. Can STEC Be a Risk Factor for Adverse Pregnancy Outcomes?
por: Scalise, María Luján, et al.
Publicado: (2022)

The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody
por: Luz, Daniela, et al.
Publicado: (2021)

The cytotoxin of Pseudomonas aeruginosa: Cytotoxicity requires proteolytic activation
por: Orlik-Eisel, Gabriele, et al.
Publicado: (1990)

Endocytosis, Cytotoxicity, and Translocation of Shiga Toxin-2 Are Stimulated by Infection of Human Intestinal (HCT-8) Monolayers With an Hypervirulent E. coli O157:H7 Lacking stx2 Gene
por: Garimano, Nicolás, et al.
Publicado: (2019)

Ouabaïne
Publicado: (1891)

The Shiga Toxin Receptor Globotriaosylceramide as Therapeutic Target in Shiga Toxin E. coli Mediated HUS
por: Feitz, Wouter J. C., et al.
Publicado: (2021)

Pseudomonas aeruginosa Cytotoxins: Mechanisms of Cytotoxicity and Impact on Inflammatory Responses
por: Wood, Stephen J., et al.
Publicado: (2023)

Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells
por: Mayr, Christian, et al.
Publicado: (2023)

Kingella kingae RtxA Cytotoxin in the Context of Other RTX Toxins
por: Filipi, Katerina, et al.
Publicado: (2022)

An Extracellular Subtilase Switch for Immune Priming in Arabidopsis
por: Ramírez, Vicente, et al.
Publicado: (2013)

Roles of Shiga Toxins in Immunopathology
por: Lee, Moo-Seung, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_q3m4pbnl4drpsth61kvf6di0p1