A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone

Mycolactone, a polyketide molecule produced by Mycobacterium ulcerans, is the etiological agent of Buruli ulcer. This lipid toxin is endowed with pleiotropic effects, presents cytotoxic effects at high doses, and notably plays a pivotal role in host response upon colonization by the bacillus. Most r...

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Detalles Bibliográficos
Autores principales: Song, Ok-Ryul, Kim, Han-Byul, Jouny, Samuel, Ricard, Isabelle, Vandeputte, Alexandre, Deboosere, Nathalie, Marion, Estelle, Queval, Christophe J., Lesport, Pierre, Bourinet, Emmanuel, Henrion, Daniel, Oh, Seog Bae, Lebon, Guillaume, Sandoz, Guillaume, Yeramian, Edouard, Marsollier, Laurent, Brodin, Priscille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535174/
https://www.ncbi.nlm.nih.gov/pubmed/28718822
http://dx.doi.org/10.3390/toxins9070227

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