Cargando…
Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature
BACKGROUND: Fibroepithelioma of Pinkus (FeP) is an uncommon and controversial skin lesion, sharing features of both basal cell carcinoma (BCC) and trichoepithelioma. In this article, we present a case of FeP and synthesise current concepts on the etiopathogenesis, diagnosis and treatment of this unc...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
ID Design 2012/DOOEL Skopje
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535652/ https://www.ncbi.nlm.nih.gov/pubmed/28785327 http://dx.doi.org/10.3889/oamjms.2017.079 |
_version_ | 1783253880376655872 |
---|---|
author | Mihai, Mara Madalina Voicu, Cristiana Lupu, Mihai Koleva, Nely Patterson, James W. Lotti, Torello Lotti, Jacopo França, Katlein Batashki, Atanas Bakardzhiev, Ilko Wollina, Uwe Tchernev, Georgi |
author_facet | Mihai, Mara Madalina Voicu, Cristiana Lupu, Mihai Koleva, Nely Patterson, James W. Lotti, Torello Lotti, Jacopo França, Katlein Batashki, Atanas Bakardzhiev, Ilko Wollina, Uwe Tchernev, Georgi |
author_sort | Mihai, Mara Madalina |
collection | PubMed |
description | BACKGROUND: Fibroepithelioma of Pinkus (FeP) is an uncommon and controversial skin lesion, sharing features of both basal cell carcinoma (BCC) and trichoepithelioma. In this article, we present a case of FeP and synthesise current concepts on the etiopathogenesis, diagnosis and treatment of this uncommon tumour. CASE REPORT: We report the case of an 88-year-old male patient presenting to the dermatology clinic for a sharply demarcated, pink, exophytic cutaneous tumour situated in the left inguinal region. The histopathological examination performed after complete surgical excision of the lesion revealed a diagnosis of FeP. A systematic review of the literature was conducted. The terms `fibroepithelioma` and `Pinkus` have been searched in bibliographical databases, including PubMed and Google Scholar, without time limitation up to February 15th, 2017. Seventy-nine articles that fulfilled all the required conditions were identified. Relevant citations and additional articles identified from references have been assessed. The systematic review included a total number of 452 cases of FeP. CONCLUSION: Even though FeP is considered a relatively rare tumour, its true incidence rate might be higher than previously believed. The clinical aspects of the lesion described in this paper and its location in the left lower quadrant of the abdomen are classic features of FeP. Histopathologic examination revealed features of both BCC and trichoepithelioma. Further epidemiological studies are required to clarify whether patients with FEP should be screened for the occurrence of other malignancies. |
format | Online Article Text |
id | pubmed-5535652 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | ID Design 2012/DOOEL Skopje |
record_format | MEDLINE/PubMed |
spelling | pubmed-55356522017-08-07 Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature Mihai, Mara Madalina Voicu, Cristiana Lupu, Mihai Koleva, Nely Patterson, James W. Lotti, Torello Lotti, Jacopo França, Katlein Batashki, Atanas Bakardzhiev, Ilko Wollina, Uwe Tchernev, Georgi Open Access Maced J Med Sci Case Report BACKGROUND: Fibroepithelioma of Pinkus (FeP) is an uncommon and controversial skin lesion, sharing features of both basal cell carcinoma (BCC) and trichoepithelioma. In this article, we present a case of FeP and synthesise current concepts on the etiopathogenesis, diagnosis and treatment of this uncommon tumour. CASE REPORT: We report the case of an 88-year-old male patient presenting to the dermatology clinic for a sharply demarcated, pink, exophytic cutaneous tumour situated in the left inguinal region. The histopathological examination performed after complete surgical excision of the lesion revealed a diagnosis of FeP. A systematic review of the literature was conducted. The terms `fibroepithelioma` and `Pinkus` have been searched in bibliographical databases, including PubMed and Google Scholar, without time limitation up to February 15th, 2017. Seventy-nine articles that fulfilled all the required conditions were identified. Relevant citations and additional articles identified from references have been assessed. The systematic review included a total number of 452 cases of FeP. CONCLUSION: Even though FeP is considered a relatively rare tumour, its true incidence rate might be higher than previously believed. The clinical aspects of the lesion described in this paper and its location in the left lower quadrant of the abdomen are classic features of FeP. Histopathologic examination revealed features of both BCC and trichoepithelioma. Further epidemiological studies are required to clarify whether patients with FEP should be screened for the occurrence of other malignancies. ID Design 2012/DOOEL Skopje 2017-07-19 /pmc/articles/PMC5535652/ /pubmed/28785327 http://dx.doi.org/10.3889/oamjms.2017.079 Text en Copyright: © 2017 Mara Madalina Mihai, Cristiana Voicu, Mihai Lupu, Nely Koleva, James W. Patterson, Torello Lotti, Jacopo Lotti, Katlein França, Atanas Batashki, Ilko Bakardzhiev, Uwe Wollina, Georgi Tchernev. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). |
spellingShingle | Case Report Mihai, Mara Madalina Voicu, Cristiana Lupu, Mihai Koleva, Nely Patterson, James W. Lotti, Torello Lotti, Jacopo França, Katlein Batashki, Atanas Bakardzhiev, Ilko Wollina, Uwe Tchernev, Georgi Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature |
title | Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature |
title_full | Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature |
title_fullStr | Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature |
title_full_unstemmed | Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature |
title_short | Fibroepithelioma of Pinkus (FeP) Located in the Left Lower Quadrant of the Abdomen - Case Report and Review of the Literature |
title_sort | fibroepithelioma of pinkus (fep) located in the left lower quadrant of the abdomen - case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535652/ https://www.ncbi.nlm.nih.gov/pubmed/28785327 http://dx.doi.org/10.3889/oamjms.2017.079 |
work_keys_str_mv | AT mihaimaramadalina fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT voicucristiana fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT lupumihai fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT kolevanely fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT pattersonjamesw fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT lottitorello fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT lottijacopo fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT francakatlein fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT batashkiatanas fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT bakardzhievilko fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT wollinauwe fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature AT tchernevgeorgi fibroepitheliomaofpinkusfeplocatedintheleftlowerquadrantoftheabdomencasereportandreviewoftheliterature |