Cargando…
A Primary Cutaneous Nocardiosis of the Hand
BACKGROUND: Nocardiosis is caused by an aerobic actinomycete, most commonly introduced through the respiratory tract. The Nocardiae are gram-positive, partially acid-fast bacteria. Primary cutaneous nocardiosis infections are rare and caused by the traumatic introduction of organisms percutaneously....
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
ID Design 2012/DOOEL Skopje
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535660/ https://www.ncbi.nlm.nih.gov/pubmed/28785335 http://dx.doi.org/10.3889/oamjms.2017.106 |
_version_ | 1783253882241024000 |
---|---|
author | Camozzota, Camilla Goldman, Alberto Tchernev, Georgi Lotti, Torello Wollina, Uwe |
author_facet | Camozzota, Camilla Goldman, Alberto Tchernev, Georgi Lotti, Torello Wollina, Uwe |
author_sort | Camozzota, Camilla |
collection | PubMed |
description | BACKGROUND: Nocardiosis is caused by an aerobic actinomycete, most commonly introduced through the respiratory tract. The Nocardiae are gram-positive, partially acid-fast bacteria. Primary cutaneous nocardiosis infections are rare and caused by the traumatic introduction of organisms percutaneously. The manifestation is usually an opportunistic infection. Cutaneous involvement may develop as one of four types: mycetoma, lymphocutaneous infection, superficial skin infection, or systemic disease with cutaneous involvement. Diagnosis and evaluation of appropriate specimens are principally by culture. CASE PRESENTATION: A 55-year-old female patient with diabetes type II presented with chronic skin lesions on the hand. Otherwise, her medical history was unremarkable. There were no signs of systemic disease. Direct examination of swabs demonstrated gramme bacteria and culture on Sabouraud agar was positive for Nocardia spp. The specimen of nocardiae was not identified. The patient was treated during nine months with sulfamethoxazole plus trimethoprim. There was an important clinical improvement of the cutaneous aspect of the lesions in hand. Some scars and fibrosis remained after nocardiosis. CONCLUSIONS: Primary cutaneous nocardiosis of the hand is a rare condition. The clinical diagnosis is difficult, and culture is mandatory. |
format | Online Article Text |
id | pubmed-5535660 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | ID Design 2012/DOOEL Skopje |
record_format | MEDLINE/PubMed |
spelling | pubmed-55356602017-08-07 A Primary Cutaneous Nocardiosis of the Hand Camozzota, Camilla Goldman, Alberto Tchernev, Georgi Lotti, Torello Wollina, Uwe Open Access Maced J Med Sci Case Report BACKGROUND: Nocardiosis is caused by an aerobic actinomycete, most commonly introduced through the respiratory tract. The Nocardiae are gram-positive, partially acid-fast bacteria. Primary cutaneous nocardiosis infections are rare and caused by the traumatic introduction of organisms percutaneously. The manifestation is usually an opportunistic infection. Cutaneous involvement may develop as one of four types: mycetoma, lymphocutaneous infection, superficial skin infection, or systemic disease with cutaneous involvement. Diagnosis and evaluation of appropriate specimens are principally by culture. CASE PRESENTATION: A 55-year-old female patient with diabetes type II presented with chronic skin lesions on the hand. Otherwise, her medical history was unremarkable. There were no signs of systemic disease. Direct examination of swabs demonstrated gramme bacteria and culture on Sabouraud agar was positive for Nocardia spp. The specimen of nocardiae was not identified. The patient was treated during nine months with sulfamethoxazole plus trimethoprim. There was an important clinical improvement of the cutaneous aspect of the lesions in hand. Some scars and fibrosis remained after nocardiosis. CONCLUSIONS: Primary cutaneous nocardiosis of the hand is a rare condition. The clinical diagnosis is difficult, and culture is mandatory. ID Design 2012/DOOEL Skopje 2017-07-20 /pmc/articles/PMC5535660/ /pubmed/28785335 http://dx.doi.org/10.3889/oamjms.2017.106 Text en Copyright: © 2017 Camilla Camozzota, Alberto Goldman, Georgi Tchernev, Torello Lotti, Uwe Wollina. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). |
spellingShingle | Case Report Camozzota, Camilla Goldman, Alberto Tchernev, Georgi Lotti, Torello Wollina, Uwe A Primary Cutaneous Nocardiosis of the Hand |
title | A Primary Cutaneous Nocardiosis of the Hand |
title_full | A Primary Cutaneous Nocardiosis of the Hand |
title_fullStr | A Primary Cutaneous Nocardiosis of the Hand |
title_full_unstemmed | A Primary Cutaneous Nocardiosis of the Hand |
title_short | A Primary Cutaneous Nocardiosis of the Hand |
title_sort | primary cutaneous nocardiosis of the hand |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535660/ https://www.ncbi.nlm.nih.gov/pubmed/28785335 http://dx.doi.org/10.3889/oamjms.2017.106 |
work_keys_str_mv | AT camozzotacamilla aprimarycutaneousnocardiosisofthehand AT goldmanalberto aprimarycutaneousnocardiosisofthehand AT tchernevgeorgi aprimarycutaneousnocardiosisofthehand AT lottitorello aprimarycutaneousnocardiosisofthehand AT wollinauwe aprimarycutaneousnocardiosisofthehand AT camozzotacamilla primarycutaneousnocardiosisofthehand AT goldmanalberto primarycutaneousnocardiosisofthehand AT tchernevgeorgi primarycutaneousnocardiosisofthehand AT lottitorello primarycutaneousnocardiosisofthehand AT wollinauwe primarycutaneousnocardiosisofthehand |