Cargando…

Lovastatin Inhibits Cancer Stem Cells and Sensitizes to Chemo- and Photodynamic Therapy in Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated malignancy occurring at high incidence in Southeast Asia and southern China. In spite of the good response to radio- and chemo-therapy at the early stage, resistance and recurrence develop in NPC patients in the advanced setting. Can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peng, Yikun, He, Guangchun, Tang, Da, Xiong, Li, Wen, Yu, Miao, Xiongying, Hong, Zhangyong, Yao, Hui, Chen, Chao, Yan, Shichao, Lu, Lu, Yang, Yingke, Li, Qinglong, Deng, Xiyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535721/ https://www.ncbi.nlm.nih.gov/pubmed/28775785 http://dx.doi.org/10.7150/jca.19100

Ejemplares similares

PAI1: a novel PP1‐interacting protein that mediates human plasma's anti‐apoptotic effect in endothelial cells
por: Yao, Hui, et al.
Publicado: (2017)

Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis
por: Yang, Tao, et al.
Publicado: (2016)

3D modeling of cancer stem cell niche
por: He, Jun, et al.
Publicado: (2017)

Lovastatin Inhibits EMT and Metastasis of Triple-Negative Breast Cancer Stem Cells Through Dysregulation of Cytoskeleton-Associated Proteins
por: Zheng, Chanjuan, et al.
Publicado: (2021)

Reversal of HER2 Negativity: An Unexpected Role for Lovastatin in Triple-Negative Breast Cancer Stem Cells
por: Yi, Huimei, et al.
Publicado: (2020)

Proteomic Analysis of the Molecular Mechanism of Lovastatin Inhibiting the Growth of Nasopharyngeal Carcinoma Cells
por: Mo, Yongzhen, et al.
Publicado: (2019)

Hexokinase 2 Is a Pivot for Lovastatin-induced Glycolysis-to-Autophagy Reprogramming in Triple-Negative Breast Cancer Cells
por: Xue, Lian, et al.
Publicado: (2022)

Structural basis for the biosynthesis of lovastatin
por: Wang, Jialiang, et al.
Publicado: (2021)

Nucleolar stress: is there a reverse version?
por: Lu, Lu, et al.
Publicado: (2018)

Combination of Fluorescence-Guided Surgery With Photodynamic Therapy for the Treatment of Cancer
por: He, Jun, et al.
Publicado: (2017)

Synergistically Enhanced Inhibitory Effects of Pullulan Nanoparticle-Mediated Co-Delivery of Lovastatin and Doxorubicin to Triple-Negative Breast Cancer Cells
por: Wu, Di, et al.
Publicado: (2019)

Ternary cocktail nanoparticles for sequential chemo-photodynamic therapy
por: Fan, Li, et al.
Publicado: (2017)

Dual-Activated Nano-Prodrug for Chemo-Photodynamic Combination Therapy of Breast Cancer
por: Lu, Ziyao, et al.
Publicado: (2022)

Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
por: Chan, David Y. L., et al.
Publicado: (2007)

Triple-negative breast cancer: is there a treatment on the horizon?
por: Yao, Hui, et al.
Publicado: (2016)

Self-assembled organic nanorods for dual chemo-photodynamic therapies
por: Li, Yuanyuan, et al.
Publicado: (2018)

GSH-sensitive polymeric prodrug: Synthesis and loading with photosensitizers as nanoscale chemo-photodynamic anti-cancer nanomedicine
por: Luo, Lei, et al.
Publicado: (2022)

XRCC1 Is a Promising Predictive Biomarker and Facilitates Chemo-Resistance in Gallbladder Cancer
por: Wu, Zhengchun, et al.
Publicado: (2020)

Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy
por: Du, Jianbing, et al.
Publicado: (2021)

Photoactivation of Chemotherapeutic Agents with Cerenkov Radiation for Chemo-Photodynamic Therapy
por: Gallaga-González, Uriel, et al.
Publicado: (2022)

Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome
por: Hao, Dapeng, et al.
Publicado: (2019)

A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy
por: Wu, Yihan, et al.
Publicado: (2022)

Magnetic And pH Dual-Responsive Nanoparticles For Synergistic Drug-Resistant Breast Cancer Chemo/Photodynamic Therapy
por: Wang, Dan, et al.
Publicado: (2019)

EVI1 promotes epithelial-to-mesenchymal transition, cancer stem cell features and chemo−/radioresistance in nasopharyngeal carcinoma
por: Lu, Yaoyong, et al.
Publicado: (2019)

Microbial Production and Biomedical Applications of Lovastatin
por: Seenivasan, A., et al.
Publicado: (2008)

The role of lovastatin in the attenuation of COVID-19
por: Karampoor, Sajad, et al.
Publicado: (2021)

Effects of Lovastatin on Brain Cancer Cells
por: Amadasu, Efosa, et al.
Publicado: (2022)

Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy
por: Lin, Xiongjie, et al.
Publicado: (2022)

Differences Between Lovastatin and Simvastatin Hydrolysis in Healthy Male and Female Volunteers: Gut Hydrolysis of Lovastatin is Twice that of Simvastatin
por: Vree, Tom B., et al.
Publicado: (2003)

Synergy of Chemo- and Photodynamic Therapies with C(60) Fullerene-Doxorubicin Nanocomplex
por: Grebinyk, Anna, et al.
Publicado: (2019)

Cell membranes targeted unimolecular prodrug for programmatic photodynamic-chemo therapy
por: Yuan, Jie, et al.
Publicado: (2021)

Tumor Targeting Chemo- and Photodynamic Therapy Packaged in Albumin for Enhanced Anti-Tumor Efficacy
por: Zheng, Ke, et al.
Publicado: (2020)

Bacterial outer membrane vesicles-based therapeutic platform eradicates triple-negative breast tumor by combinational photodynamic/chemo-/immunotherapy
por: Li, Yongjiang, et al.
Publicado: (2022)

Guiding Appropriate Timing of Laser Irradiation by Polymeric Micelles for Maximizing Chemo-Photodynamic Therapy
por: Zhu, Yun, et al.
Publicado: (2020)

Involvement of Non-Coding RNAs in Chemo- and Radioresistance of Nasopharyngeal Carcinoma
por: Xiao, Jiaxin, et al.
Publicado: (2021)

ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy
por: Wan, Zhuo, et al.
Publicado: (2022)

Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma
por: Pan, Yunbao, et al.
Publicado: (2013)

Lovastatin promotes the self-renewal of murine and primate spermatogonial stem cells
por: Li, Chaohui, et al.
Publicado: (2023)

Lovastatin Protects against Experimental Plague in Mice
por: Ayyadurai, Saravanan, et al.
Publicado: (2010)

Improved bioavailability through floating microspheres of lovastatin
por: Kumar, S., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_uvl4trkks1n40ulnthk49v90v0