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Pharmacogenomic Variants May Influence the Urinary Excretion of Novel Kidney Injury Biomarkers in Patients Receiving Cisplatin

Nephrotoxicity is a dose limiting side effect associated with the use of cisplatin in the treatment of solid tumors. The degree of nephrotoxicity is dictated by the selective accumulation of cisplatin in renal tubule cells due to: (1) uptake by organic cation transporter 2 (OCT2) and copper transpor...

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Detalles Bibliográficos
Autores principales:	Chang, Cara, Hu, Yichun, Hogan, Susan L., Mercke, Nickie, Gomez, Madeleine, O’Bryant, Cindy, Bowles, Daniel W., George, Blessy, Wen, Xia, Aleksunes, Lauren M., Joy, Melanie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535826/ https://www.ncbi.nlm.nih.gov/pubmed/28640195 http://dx.doi.org/10.3390/ijms18071333

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