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5-(3′,4′-Dihydroxyphenyl-γ-valerolactone), a Major Microbial Metabolite of Proanthocyanidin, Attenuates THP-1 Monocyte-Endothelial Adhesion

Several metabolomics of polymeric flavan-3-ols have reported that proanthocyanidins are extensively metabolized by gut microbiota. 5-(3′,4′-dihydroxyphenyl)-γ-valerolactone (DHPV) has been reported to be the major microbial metabolite of proanthocyanidins. We demonstrated that DHPV has stronger prev...

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Detalles Bibliográficos
Autores principales: Lee, Charles C., Kim, Jong Hun, Kim, Ji Seung, Oh, Yun Sil, Han, Seung Min, Yoon Park, Jung Han, Lee, Ki Won, Lee, Chang Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535856/
https://www.ncbi.nlm.nih.gov/pubmed/28672844
http://dx.doi.org/10.3390/ijms18071363