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Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy
The phototoxic effect of hypericin can be utilized for Photodynamic Therapy (PDT) of cancer. After intravenous application and systemic distribution of the drug in the patient’s body, the tumor site is exposed to light. Subsequently, toxic reactive oxygen species (ROS) are generated, inducing tumor...
Autores principales: | Mühleisen, Laura, Alev, Magdalena, Unterweger, Harald, Subatzus, Daniel, Pöttler, Marina, Friedrich, Ralf P., Alexiou, Christoph, Janko, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535881/ https://www.ncbi.nlm.nih.gov/pubmed/28661430 http://dx.doi.org/10.3390/ijms18071388 |
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