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Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway

Dysfunction of the N-methyl-d-aspartate (NMDA) receptor has been implicated in the pathogenesis of schizophrenia. Although agonists for the glycine-binding sites of NMDA receptors have potential as new medication for schizophrenia, their modulation of antipsychotic-induced extrapyramidal side effect...

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Detalles Bibliográficos
Autores principales:	Shimizu, Saki, Sogabe, Shunsaku, Yanagisako, Ryoto, Inada, Akiyoshi, Yamanaka, Megumi, Iha, Higor A., Ohno, Yukihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535908/ https://www.ncbi.nlm.nih.gov/pubmed/28671605 http://dx.doi.org/10.3390/ijms18071416

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