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Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays
In most p53 wild-type human cell types, radiosensitivity evaluated by the colony formation assay predominantly reflects stress-induced premature senescence (SIPS) and not cell death (Int. J. Mol. Sci. 2017, 18, 928). SIPS is a growth-arrested state in which the cells acquire flattened and enlarged m...
Autores principales: | Mirzayans, Razmik, Andrais, Bonnie, Murray, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535951/ https://www.ncbi.nlm.nih.gov/pubmed/28684684 http://dx.doi.org/10.3390/ijms18071460 |
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