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The Application of REDOR NMR to Understand the Conformation of Epothilone B
The structural information of small therapeutic compounds complexed in biological matrices is important for drug developments. However, structural studies on ligands bound to such a large and dynamic system as microtubules are still challenging. This article reports an application of the solid-state...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535963/ https://www.ncbi.nlm.nih.gov/pubmed/28698492 http://dx.doi.org/10.3390/ijms18071472 |