Mitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus

Mitochondrial dysfunction plays a central role in the neuropathology associated with status epilepticus (SE) and is implicated in the development of epilepsy. While excitotoxic mechanisms are well-known mediators affecting mitochondrial health following SE, whether hyperactivation of poly(ADP-ribose...

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Detalles Bibliográficos
Autores principales: Lai, Yi-Chen, Baker, J. Scott, Donti, Taraka, Graham, Brett H., Craigen, William J., Anderson, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535992/
https://www.ncbi.nlm.nih.gov/pubmed/28704930
http://dx.doi.org/10.3390/ijms18071502

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