Cargando…

Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation

Melanoma is the most malignant form of skin cancer and is associated with a very poor prognosis. The aim of this study was to evaluate the apoptotic effects of cudraflavone C on A375.S2 melanoma cells and to determine the underlying mechanisms involved in apoptosis. Cell viability was determined usi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Chiang-Wen, Yen, Feng-Lin, Ko, Horng-Huey, Li, Shu-Yu, Chiang, Yao-Chang, Lee, Ming-Hsueh, Tsai, Ming-Horng, Hsu, Lee-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535998/ https://www.ncbi.nlm.nih.gov/pubmed/28703746 http://dx.doi.org/10.3390/ijms18071508

Ejemplares similares

Mechanism of Lakoochin A Inducing Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS and MAPKs Pathway
por: Peng, Kuo-Ti, et al.
Publicado: (2018)

Extracts of Artocarpus communis Induce Mitochondria-Associated Apoptosis via Pro-oxidative Activity in Human Glioblastoma Cells
por: Lee, Chiang-Wen, et al.
Publicado: (2018)

Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells
por: Tsai, Ming-Horng, et al.
Publicado: (2017)

Correction: Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells
por: Tsai, Ming-Horng, et al.
Publicado: (2019)

Curcumin Nanoparticles Ameliorate ICAM-1 Expression in TNF-α-Treated Lung Epithelial Cells through p47 (phox) and MAPKs/AP-1 Pathways
por: Yen, Feng-Lin, et al.
Publicado: (2013)

Urban Particulate Matter Enhances ROS/IL-6/COX-II Production by Inhibiting MicroRNA-137 in Synovial Fibroblast of Rheumatoid Arthritis
por: Tsai, Ming-Horng, et al.
Publicado: (2020)

Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress
por: Lin, Zih-Chan, et al.
Publicado: (2016)

Cudraflavone B induces human glioblastoma cells apoptosis via ER stress-induced autophagy
por: Pan, Jinlin, et al.
Publicado: (2023)

CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression
por: Tsai, Ming-Horng, et al.
Publicado: (2017)

The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro
por: Haasler, Lisa, et al.
Publicado: (2021)

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM
por: Woo, Joong-Seok, et al.
Publicado: (2020)

Extracts of Artocarpus communis Decrease α-Melanocyte Stimulating Hormone-Induced Melanogenesis through Activation of ERK and JNK Signaling Pathways
por: Fu, Yi-Tzu, et al.
Publicado: (2014)

Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway
por: Soo, Hsien-Chuen, et al.
Publicado: (2017)

Norartocarpetin from a folk medicine Artocarpus communis plays a melanogenesis inhibitor without cytotoxicity in B16F10 cell and skin irritation in mice
por: Ko, Horng-Huey, et al.
Publicado: (2013)

Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib
por: Hui, Kwai Fung, et al.
Publicado: (2015)

Melanogenesis Inhibitor(s) from Phyla nodiflora Extract
por: Yen, Feng-Lin, et al.
Publicado: (2012)

Effects of ginsenoside Rg3 on apoptosis in A375.S2 melanoma cells
por: Kim, Joo Hyoung, et al.
Publicado: (2019)

Triclosan induces ROS-dependent cell death and autophagy in A375 melanoma cells
por: Jin, Jing, et al.
Publicado: (2020)

Norcantharidin Induces Human Melanoma A375-S2 Cell Apoptosis through Mitochondrial and Caspase Pathways
por: An, Wei-wei, et al.
Publicado: (2004)

Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction
por: Lee, Chiang-Wen, et al.
Publicado: (2016)

Effect of Artocarpus communis Extract on UVB Irradiation-Induced Oxidative Stress and Inflammation in Hairless Mice
por: Lee, Chiang-Wen, et al.
Publicado: (2013)

The Induction of Apoptosis in A375 Malignant Melanoma Cells by Sutherlandia frutescens
por: van der Walt, Nicola B., et al.
Publicado: (2016)

Neurological Complications after Neonatal Bacteremia: The Clinical Characteristics, Risk Factors, and Outcomes
por: Chu, Shih-Ming, et al.
Publicado: (2014)

Sensitivity of allyl isothiocyanate to induce apoptosis via ER stress and the mitochondrial pathway upon ROS production in colorectal adenocarcinoma cells
por: Chiang, Jo-Hua, et al.
Publicado: (2020)

Down-Regulation of Deacetylase HDAC6 Inhibits the Melanoma Cell Line A375.S2 Growth through ROS-Dependent Mitochondrial Pathway
por: Bai, Jun, et al.
Publicado: (2015)

Curcumin Induces Apoptosis of Chemoresistant Lung Cancer Cells via ROS-Regulated p38 MAPK Phosphorylation
por: Wu, Ming-Fang, et al.
Publicado: (2022)

Polymicrobial Bloodstream Infection in Neonates: Microbiology, Clinical Characteristics, and Risk Factors
por: Tsai, Ming-Horng, et al.
Publicado: (2014)

Incidence, Clinical Characteristics and Attributable Mortality of Persistent Bloodstream Infection in the Neonatal Intensive Care Unit
por: Hsu, Jen-Fu, et al.
Publicado: (2015)

Characteristics of neonates with culture-proven bloodstream infection who have low levels of C-reactive protein (≦10 mg/L)
por: Lai, Mei-Yin, et al.
Publicado: (2015)

Nitrogen Adsorption and Characteristics of Iron, Cobalt, and Nickel Oxides Impregnated on SBA-15 Mesoporous Silica
por: Tsai, Jiun-Horng, et al.
Publicado: (2023)

Effect of hypoxia factors gene silencing on ROS production and metabolic status of A375 malignant melanoma cells
por: Špaková, Ivana, et al.
Publicado: (2021)

Infectious Complications and Morbidities After Neonatal Bloodstream Infections: An Observational Cohort Study
por: Tsai, Ming-Horng, et al.
Publicado: (2016)

Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy
por: Lee, Tzu-Lin, et al.
Publicado: (2020)

Incidence, clinical features, and implications on outcomes of neonatal late-onset sepsis with concurrent infectious focus
por: Wu, I-Hsyuan, et al.
Publicado: (2017)

HPLC-Fingerprints and Antioxidant Constituents of Phyla nodiflora
por: Lin, Fang-Ju, et al.
Publicado: (2014)

Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells
por: Lee, I-Ta, et al.
Publicado: (2012)

Comparison of the incidence, clinical features and outcomes of invasive candidiasis in children and neonates
por: Hsu, Jen-Fu, et al.
Publicado: (2018)

Surfactin from Bacillus subtilis attenuates ambient air particulate matter-promoted human oral cancer cells metastatic potential
por: Vo, Thi Thuy Tien, et al.
Publicado: (2020)

The MAPK pathway as an apoptosis enhancer in melanoma
por: Haydn, Johannes M., et al.
Publicado: (2014)

Synergistic Apoptosis-Inducing Effects on A375 Human Melanoma Cells of Natural Borneol and Curcumin
por: Chen, Jianping, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7422tv87hjrufj1bo6iubk3n0v