Cargando…
DNA Damage Tolerance by Eukaryotic DNA Polymerase and Primase PrimPol
PrimPol is a human deoxyribonucleic acid (DNA) polymerase that also possesses primase activity and is involved in DNA damage tolerance, the prevention of genome instability and mitochondrial DNA maintenance. In this review, we focus on recent advances in biochemical and crystallographic studies of P...
Autores principales: | Boldinova, Elizaveta O., Wanrooij, Paulina H., Shilkin, Evgeniy S., Wanrooij, Sjoerd, Makarova, Alena V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536071/ https://www.ncbi.nlm.nih.gov/pubmed/28754021 http://dx.doi.org/10.3390/ijms18071584 |
Ejemplares similares
-
Optimization of the expression, purification and polymerase activity reaction conditions of recombinant human PrimPol
por: Boldinova, Elizaveta O., et al.
Publicado: (2017) -
Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-links
por: Boldinova, Elizaveta O., et al.
Publicado: (2021) -
Strand Displacement Activity of PrimPol
por: Boldinova, Elizaveta O., et al.
Publicado: (2020) -
Structure and mechanism of human PrimPol, a DNA polymerase with primase activity
por: Rechkoblit, Olga, et al.
Publicado: (2016) -
Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase
por: Agudo, Rubén, et al.
Publicado: (2017)