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A Rare Case of Adult Rhabdomyosarcoma
BACKGROUND: Rhabdomyosarcoma is a rare, soft tissue malignancy, diagnosed particularly in adults. It commonly metastasizes to the bone marrow. We present a rare case of an adult rhabdomyosarcoma which illustrates the importance of magnetic resonance imaging in identifying early changes in the intern...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536128/ https://www.ncbi.nlm.nih.gov/pubmed/28811847 http://dx.doi.org/10.12659/PJR.901967 |
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author | Sparreboom, Benjamin Litton, Brendan Yaxley, Julian |
author_facet | Sparreboom, Benjamin Litton, Brendan Yaxley, Julian |
author_sort | Sparreboom, Benjamin |
collection | PubMed |
description | BACKGROUND: Rhabdomyosarcoma is a rare, soft tissue malignancy, diagnosed particularly in adults. It commonly metastasizes to the bone marrow. We present a rare case of an adult rhabdomyosarcoma which illustrates the importance of magnetic resonance imaging in identifying early changes in the internal bone structure. CASE REPORT: A 50-year-old male presented with acute urinary retention. The patient initially had a CT scan of the lumbar spine which only revealed a protrusion of the L5–S1 intervertebral disc and no apparent cause for the patient’s symptoms. One week later, an MRI was performed which showed extensive bone marrow metastases throughout the lumbar spine and a soft tissue mass in the lower sacral region. The bony metastases were not evident on the CT scan and the soft tissue mass was out of the coverage area of the CT. Subsequent biopsy of the soft tissue mass was performed and histopathology concluded the tissue to be a rhabdomyosarcoma. Unfortunately, the patient died one week after diagnosis. CONCLUSIONS: Although adult rhabdomyosarcomas are very rare, this case highlights the advantage of MRI over CT in identifying early changes in the internal bone structure. Therefore, CT should not be relied upon to exclude bony metastases, particularly in the setting of primary cancer with a known tendency to metastasize to the bone marrow. |
format | Online Article Text |
id | pubmed-5536128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-55361282017-08-15 A Rare Case of Adult Rhabdomyosarcoma Sparreboom, Benjamin Litton, Brendan Yaxley, Julian Pol J Radiol Case Report BACKGROUND: Rhabdomyosarcoma is a rare, soft tissue malignancy, diagnosed particularly in adults. It commonly metastasizes to the bone marrow. We present a rare case of an adult rhabdomyosarcoma which illustrates the importance of magnetic resonance imaging in identifying early changes in the internal bone structure. CASE REPORT: A 50-year-old male presented with acute urinary retention. The patient initially had a CT scan of the lumbar spine which only revealed a protrusion of the L5–S1 intervertebral disc and no apparent cause for the patient’s symptoms. One week later, an MRI was performed which showed extensive bone marrow metastases throughout the lumbar spine and a soft tissue mass in the lower sacral region. The bony metastases were not evident on the CT scan and the soft tissue mass was out of the coverage area of the CT. Subsequent biopsy of the soft tissue mass was performed and histopathology concluded the tissue to be a rhabdomyosarcoma. Unfortunately, the patient died one week after diagnosis. CONCLUSIONS: Although adult rhabdomyosarcomas are very rare, this case highlights the advantage of MRI over CT in identifying early changes in the internal bone structure. Therefore, CT should not be relied upon to exclude bony metastases, particularly in the setting of primary cancer with a known tendency to metastasize to the bone marrow. International Scientific Literature, Inc. 2017-07-22 /pmc/articles/PMC5536128/ /pubmed/28811847 http://dx.doi.org/10.12659/PJR.901967 Text en © Pol J Radiol, 2017 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Sparreboom, Benjamin Litton, Brendan Yaxley, Julian A Rare Case of Adult Rhabdomyosarcoma |
title | A Rare Case of Adult Rhabdomyosarcoma |
title_full | A Rare Case of Adult Rhabdomyosarcoma |
title_fullStr | A Rare Case of Adult Rhabdomyosarcoma |
title_full_unstemmed | A Rare Case of Adult Rhabdomyosarcoma |
title_short | A Rare Case of Adult Rhabdomyosarcoma |
title_sort | rare case of adult rhabdomyosarcoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536128/ https://www.ncbi.nlm.nih.gov/pubmed/28811847 http://dx.doi.org/10.12659/PJR.901967 |
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