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Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models
Altered concentrations of monoamine neurotransmitters and metabolites have been repeatedly found in people with Down syndrome (DS, trisomy 21). Because of the limited availability of human post-mortem tissue, DS mouse models are of great interest to study these changes and the underlying neurobiolog...
Autores principales: | Dekker, Alain D., Vermeiren, Yannick, Albac, Christelle, Lana-Elola, Eva, Watson-Scales, Sheona, Gibbins, Dorota, Aerts, Tony, Van Dam, Debby, Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Potier, Marie-Claude, De Deyn, Peter P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536154/ https://www.ncbi.nlm.nih.gov/pubmed/28624415 http://dx.doi.org/10.1016/j.nbd.2017.06.007 |
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