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Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models

Altered concentrations of monoamine neurotransmitters and metabolites have been repeatedly found in people with Down syndrome (DS, trisomy 21). Because of the limited availability of human post-mortem tissue, DS mouse models are of great interest to study these changes and the underlying neurobiolog...

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Detalles Bibliográficos
Autores principales: Dekker, Alain D., Vermeiren, Yannick, Albac, Christelle, Lana-Elola, Eva, Watson-Scales, Sheona, Gibbins, Dorota, Aerts, Tony, Van Dam, Debby, Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Potier, Marie-Claude, De Deyn, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536154/
https://www.ncbi.nlm.nih.gov/pubmed/28624415
http://dx.doi.org/10.1016/j.nbd.2017.06.007

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