Cargando…

In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3

Fibroblast growth factor receptors (FGFRs) play an important role in determining cell proliferation, differentiation, migration, and survival. Although a variety of small-molecule FGFR inhibitors have been developed for cancer therapeutics, the interaction between FGFRs and FGFR inhibitors has not b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Gyoyeon, Kim, Hyeonhye, Yoon, Hojong, Song, Chiman, Lim, Dong-Kwon, Sim, Taebo, Lee, Jiyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536236/ https://www.ncbi.nlm.nih.gov/pubmed/28794627 http://dx.doi.org/10.2147/IJN.S141595

Ejemplares similares

Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs
por: Cho, Hanna, et al.
Publicado: (2021)

In vivo effects of AZD4547, a novel fibroblast growth factor receptor inhibitor, in a mouse model of endometriosis
por: Santorelli, Sara, et al.
Publicado: (2021)

The FGFR Family Inhibitor AZD4547 Exerts an Antitumor Effect in Ovarian Cancer Cells
por: Na, Yu Ran, et al.
Publicado: (2021)

Activity of fibroblast growth factor receptor inhibitors TKI258, ponatinib and AZD4547 against TPR-FGFR1 fusion
por: Qiu, Xu-Hua, et al.
Publicado: (2017)

Antitumor Effect of AZD4547 in a Fibroblast Growth Factor Receptor 2–Amplified Gastric Cancer Patient–Derived Cell Model()
por: Jang, Jiryeon, et al.
Publicado: (2017)

Targeted Inhibition of Fibroblast Growth Factor Receptor 1-GLI Through AZD4547 and GANT61 Modulates Breast Cancer Progression
por: Riaz, Syeda Kiran, et al.
Publicado: (2021)

Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer
por: Coombes, R. C., et al.
Publicado: (2022)

Safety, tolerability and pharmacokinetics of the fibroblast growth factor receptor inhibitor AZD4547 in Japanese patients with advanced solid tumours: a Phase I study
por: Saka, Hideo, et al.
Publicado: (2017)

Insight into resistance mechanisms of AZD4547 and E3810 to FGFR1 gatekeeper mutation via theoretical study
por: Liang, Donglou, et al.
Publicado: (2017)

Sulfated polysaccharide of Sepiella maindroni ink targets Akt and overcomes resistance to the FGFR inhibitor AZD4547 in bladder cancer
por: Shan, Liping, et al.
Publicado: (2019)

Author Correction: Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer
por: Coombes, R. C., et al.
Publicado: (2023)

Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer
por: Chang, Jinjia, et al.
Publicado: (2014)

FGFR inhibitor, AZD4547, impedes the stemness of mammary epithelial cells in the premalignant tissues of MMTV-ErbB2 transgenic mice
por: Zhao, Qingxia, et al.
Publicado: (2017)

AZD4547 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation: The Role of FGFR1 in Renal Tubular Epithelial Cells
por: Chen, Xuemei, et al.
Publicado: (2020)

Procaspase activating compound 1 controls tetracycline repressor-regulated gene expression system
por: Song, Chiman, et al.
Publicado: (2019)

Simultaneous Multi-Species Tracking in Live Cells with Quantum Dot Conjugates
por: Clausen, Mathias P., et al.
Publicado: (2014)

A Selective FGFR inhibitor AZD4547 suppresses RANKL/M-CSF/OPG-dependent ostoclastogenesis and breast cancer growth in the metastatic bone microenvironment
por: Kang, Jinho, et al.
Publicado: (2019)

Effects of FGFR inhibitors TKI258, BGJ398 and AZD4547 on breast cancer cells in 2D, 3D and tissue explant cultures
por: Kähkönen, T. E., et al.
Publicado: (2020)

In Vitro and In Vivo Imaging of Prostate Cancer Angiogenesis Using Anti-Vascular Endothelial Growth Factor Receptor 2 Antibody-Conjugated Quantum Dot
por: Kwon, Haejin, et al.
Publicado: (2013)

The Inhibition of the FGFR/PI3K/Akt Axis by AZD4547 Disrupts the Proangiogenic Microenvironment and Vasculogenic Mimicry Arising from the Interplay between Endothelial and Triple-Negative Breast Cancer Cells
por: Morales-Guadarrama, Gabriela, et al.
Publicado: (2023)

Enzyme-Polymers Conjugated to Quantum-Dots for Sensing Applications
por: Mansur, Alexandra, et al.
Publicado: (2011)

Hyaluronan-Conjugated Carbon Quantum Dots for Bioimaging Use
por: Karakoçak, Bedia Begüm, et al.
Publicado: (2020)

Quantum dots-labeled polymeric scaffolds for in vivo tracking of degradation and tissue formation
por: Sim, Kun Hee, et al.
Publicado: (2022)

Imaging GABA(c) Receptors with Ligand-Conjugated Quantum Dots
por: Tomlinson, Ian D., et al.
Publicado: (2007)

Targeting of Embryonic Stem Cells by Peptide-Conjugated Quantum Dots
por: Lu, Shuai, et al.
Publicado: (2010)

Conjugation of quantum dots on carbon nanotubes for medical diagnosis and treatment
por: Madani, Seyed Yazdan, et al.
Publicado: (2013)

Bio-Conjugated Quantum Dots for Cancer Research: Detection and Imaging
por: Liang, Zhengyan, et al.
Publicado: (2021)

Correction: Bio-conjugation of graphene quantum dots for targeting imaging
por: Jia, Fei, et al.
Publicado: (2019)

Multi-Color Single Particle Tracking with Quantum Dots
por: Arnspang, Eva C., et al.
Publicado: (2012)

Raman-Based in Situ Monitoring of Changes in Molecular Signatures during Mitochondrially Mediated Apoptosis
por: Shin, Hyeon Jeong, et al.
Publicado: (2019)

Recognition-Mediated Assembly of Quantum Dot Polymer Conjugates with Controlled Morphology
por: Nandwana, Vikas, et al.
Publicado: (2011)

Intein-mediated site-specific conjugation of Quantum Dots to proteins in vivo
por: Charalambous, Anna, et al.
Publicado: (2009)

AMP-Conjugated Quantum Dots: Low Immunotoxicity Both In Vitro and In Vivo
por: Dai, Tongcheng, et al.
Publicado: (2015)

Small Quantum Dots Conjugated to Nanobodies as Immunofluorescence Probes for Nanometric Microscopy
por: Wang, Yong, et al.
Publicado: (2014)

Targeting human embryonic stem cells with quantum dot-conjugated phages
por: Zhao, Wenxiu, et al.
Publicado: (2013)

Quantum dot conjugated nanobodies for multiplex imaging of protein dynamics at synapses
por: Modi, Souvik, et al.
Publicado: (2018)

Evaluation of quantum dot conjugated antibodies for immunofluorescent labelling of cellular targets
por: Francis, Jennifer E, et al.
Publicado: (2017)

Bone Morphogenetic Protein-2 Conjugated to Quantum Dot(®)s is Biologically Functional
por: Halloran, Daniel, et al.
Publicado: (2020)

Click gold quantum dots biosynthesis with conjugation of quercetin for adenocarcinoma exertion
por: Pansare, Amol V., et al.
Publicado: (2022)

Detecting Proteins in Highly Autofluorescent Cells Using Quantum Dot Antibody Conjugates
por: Orcutt, Karen M., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_ovo9movlunn0ui2e74077bamr0