Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans

The 18kDa Translocator Protein (TSPO) is the most commonly used tissue-specific marker of inflammation in positron emission tomography (PET) studies. It is expressed in myeloid cells such as microglia and macrophages, and in rodent myeloid cells expression increases with cellular activation. We asse...

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Detalles Bibliográficos
Autores principales: Owen, David R, Narayan, Nehal, Wells, Lisa, Healy, Luke, Smyth, Erica, Rabiner, Eugenii A, Galloway, Dylan, Williams, John B, Lehr, Joshua, Mandhair, Harpreet, Peferoen, Laura AN, Taylor, Peter C, Amor, Sandra, Antel, Jack P, Matthews, Paul M, Moore, Craig S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Rapid Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536262/
https://www.ncbi.nlm.nih.gov/pubmed/28530125
http://dx.doi.org/10.1177/0271678X17710182

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