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cAMP-dependent activation of protein kinase A attenuates respiratory syncytial virus-induced human airway epithelial barrier disruption
Airway epithelium forms a barrier to the outside world and has a crucial role in susceptibility to viral infections. Cyclic adenosine monophosphate (cAMP) is an important second messenger acting via two intracellular signaling molecules: protein kinase A (PKA) and the guanidine nucleotide exchange f...
Autores principales: | Rezaee, Fariba, Harford, Terri J., Linfield, Debra T., Altawallbeh, Ghaith, Midura, Ronald J., Ivanov, Andrei I., Piedimonte, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536269/ https://www.ncbi.nlm.nih.gov/pubmed/28759570 http://dx.doi.org/10.1371/journal.pone.0181876 |
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