C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease

The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out to encode the shorter CD45R0 in antigen-experienced effector/memory T cells. Th...

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Detalles Bibliográficos
Autores principales: Landskron, Johannes, Kraggerud, Sigrid M., Wik, Elisabeth, Dørum, Anne, Bjørnslett, Merete, Melum, Espen, Helland, Øystein, Bjørge, Line, Lothe, Ragnhild A., Salvesen, Helga B., Taskén, Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536273/
https://www.ncbi.nlm.nih.gov/pubmed/28759630
http://dx.doi.org/10.1371/journal.pone.0182030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536273/
https://www.ncbi.nlm.nih.gov/pubmed/28759630
http://dx.doi.org/10.1371/journal.pone.0182030

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