Cargando…

Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain

Nicotinic acetylcholine receptors containing α4 subunits (α4β2* nAChRs) are critical for nicotinic cholinergic transmission and the addictive action of nicotine. To identify specific activities of these receptors in the adult mouse brain, we coupled targeted deletion of α4 nAChR subunits with behavi...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Can, Engle, Staci E., Yan, Yijin, Weera, Marcus M., Berry, Jennifer N., Arvin, Matthew C., Zhao, Guiqing, McIntosh, J. Michael, Chester, Julia A., Drenan, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536316/
https://www.ncbi.nlm.nih.gov/pubmed/28759616
http://dx.doi.org/10.1371/journal.pone.0182142