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Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain
Nicotinic acetylcholine receptors containing α4 subunits (α4β2* nAChRs) are critical for nicotinic cholinergic transmission and the addictive action of nicotine. To identify specific activities of these receptors in the adult mouse brain, we coupled targeted deletion of α4 nAChR subunits with behavi...
Autores principales: | Peng, Can, Engle, Staci E., Yan, Yijin, Weera, Marcus M., Berry, Jennifer N., Arvin, Matthew C., Zhao, Guiqing, McIntosh, J. Michael, Chester, Julia A., Drenan, Ryan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536316/ https://www.ncbi.nlm.nih.gov/pubmed/28759616 http://dx.doi.org/10.1371/journal.pone.0182142 |
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