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Cannabinoid receptor 2-63 RR variant is independently associated with severe necroinflammation in HIV/HCV coinfected patients

OBJECTIVE: This is the first study to analyze the impact of the rs35761398 variant of the CNR2 gene leading to the substitution of GLN (Q) of codon 63 of the cannabinoid receptor 2 (CB2) with ARG (R) on the clinical presentation of chronic hepatitis in HIV/HCV coinfected patients. METHODS: Enrolled...

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Detalles Bibliográficos
Autores principales: Sagnelli, Caterina, Uberti-Foppa, Caterina, Hasson, Hamid, Bellini, Giulia, Minichini, Carmine, Salpietro, Stefania, Messina, Emanuela, Barbanotti, Diletta, Merli, Marco, Punzo, Francesca, Coppola, Nicola, Lazzarin, Adriano, Sagnelli, Evangelista, Rossi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536321/
https://www.ncbi.nlm.nih.gov/pubmed/28759568
http://dx.doi.org/10.1371/journal.pone.0181890

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