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Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity

Intolerance of uncertainty (IU) is the tendency to interpret ambiguous situations as threatening and having negative consequences, resulting in feelings of distress and anxiety. IU has been linked to a number of anxiety disorders, and anxiety felt in the face of uncertainty may result in maladaptive...

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Autores principales: Garami, Julia, Haber, Paul, Myers, Catherine E., Allen, Michael T., Misiak, Blazej, Frydecka, Dorota, Moustafa, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536349/
https://www.ncbi.nlm.nih.gov/pubmed/28759635
http://dx.doi.org/10.1371/journal.pone.0181955
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author Garami, Julia
Haber, Paul
Myers, Catherine E.
Allen, Michael T.
Misiak, Blazej
Frydecka, Dorota
Moustafa, Ahmed A.
author_facet Garami, Julia
Haber, Paul
Myers, Catherine E.
Allen, Michael T.
Misiak, Blazej
Frydecka, Dorota
Moustafa, Ahmed A.
author_sort Garami, Julia
collection PubMed
description Intolerance of uncertainty (IU) is the tendency to interpret ambiguous situations as threatening and having negative consequences, resulting in feelings of distress and anxiety. IU has been linked to a number of anxiety disorders, and anxiety felt in the face of uncertainty may result in maladaptive behaviors such as impulsive decision making. Although there is strong evidence that anxiety and impulsivity are risk factors for addiction, there is a paucity of research examining the role of IU in this disorder. The rate of opioid addiction, in particular, has been rising steadily in recent years, which necessitates deeper understanding of risk factors in order to develop effective prevention and treatment methods. The current study tested for the first time whether opioid-dependent adults are less tolerant of uncertainty compared to a healthy comparison group. Opioid dependent patients undergoing methadone maintenance therapy (n = 114) and healthy comparisons (n = 69) completed the following scales: Intolerance of Uncertainty Scale, the Barrett Impulsivity Scale, and the State Trait Anxiety Inventory. Analysis revealed that these measures were positively correlated with each other and that opioid-dependent patients had significantly higher IU scores. Regression analysis revealed that anxiety mediated the relationship between IU and impulsivity. Hierarchical moderation regression found an interaction between addiction status and impulsivity on IU scores in that the relationship between these variables was only observed in the patient group. Findings suggest that IU is a feature of addiction but does not necessarily play a unique role. Further research is needed to explore the complex relationship between traits and how they may contribute to the development and maintenance of addiction.
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spelling pubmed-55363492017-08-07 Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity Garami, Julia Haber, Paul Myers, Catherine E. Allen, Michael T. Misiak, Blazej Frydecka, Dorota Moustafa, Ahmed A. PLoS One Research Article Intolerance of uncertainty (IU) is the tendency to interpret ambiguous situations as threatening and having negative consequences, resulting in feelings of distress and anxiety. IU has been linked to a number of anxiety disorders, and anxiety felt in the face of uncertainty may result in maladaptive behaviors such as impulsive decision making. Although there is strong evidence that anxiety and impulsivity are risk factors for addiction, there is a paucity of research examining the role of IU in this disorder. The rate of opioid addiction, in particular, has been rising steadily in recent years, which necessitates deeper understanding of risk factors in order to develop effective prevention and treatment methods. The current study tested for the first time whether opioid-dependent adults are less tolerant of uncertainty compared to a healthy comparison group. Opioid dependent patients undergoing methadone maintenance therapy (n = 114) and healthy comparisons (n = 69) completed the following scales: Intolerance of Uncertainty Scale, the Barrett Impulsivity Scale, and the State Trait Anxiety Inventory. Analysis revealed that these measures were positively correlated with each other and that opioid-dependent patients had significantly higher IU scores. Regression analysis revealed that anxiety mediated the relationship between IU and impulsivity. Hierarchical moderation regression found an interaction between addiction status and impulsivity on IU scores in that the relationship between these variables was only observed in the patient group. Findings suggest that IU is a feature of addiction but does not necessarily play a unique role. Further research is needed to explore the complex relationship between traits and how they may contribute to the development and maintenance of addiction. Public Library of Science 2017-07-31 /pmc/articles/PMC5536349/ /pubmed/28759635 http://dx.doi.org/10.1371/journal.pone.0181955 Text en © 2017 Garami et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Garami, Julia
Haber, Paul
Myers, Catherine E.
Allen, Michael T.
Misiak, Blazej
Frydecka, Dorota
Moustafa, Ahmed A.
Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity
title Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity
title_full Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity
title_fullStr Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity
title_full_unstemmed Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity
title_short Intolerance of uncertainty in opioid dependency – Relationship with trait anxiety and impulsivity
title_sort intolerance of uncertainty in opioid dependency – relationship with trait anxiety and impulsivity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536349/
https://www.ncbi.nlm.nih.gov/pubmed/28759635
http://dx.doi.org/10.1371/journal.pone.0181955
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