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Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes

OBJECTIVE: To investigate differences in clinical and angiographic outcomes between patients with acute myocardial infarction with red and white thrombi. METHODS: A total of 137 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary interventions were inclu...

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Autores principales: Yang, Yapan, Li, Jingchao, Xu, Wenke, Dong, Shujuan, Yu, Haijia, Song, Huihui, Chu, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536757/
https://www.ncbi.nlm.nih.gov/pubmed/27834302
http://dx.doi.org/10.1177/0300060516667373
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author Yang, Yapan
Li, Jingchao
Xu, Wenke
Dong, Shujuan
Yu, Haijia
Song, Huihui
Chu, Yingjie
author_facet Yang, Yapan
Li, Jingchao
Xu, Wenke
Dong, Shujuan
Yu, Haijia
Song, Huihui
Chu, Yingjie
author_sort Yang, Yapan
collection PubMed
description OBJECTIVE: To investigate differences in clinical and angiographic outcomes between patients with acute myocardial infarction with red and white thrombi. METHODS: A total of 137 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary interventions were included. Thrombus material was classified as white or red based on its pathology. Information on characteristics of thrombi was available for 97 (70.8%) patients. RESULTS: The total ischaemic time was significantly longer in the red thrombus group compared with the white thrombus group. The incidence of major adverse cardiovascular events in hospital was higher in the red thrombus group than in the white thrombus group (15.6% vs 0%). Multivariable logistic analysis showed that the total ischaemic time was the only predictor of thrombus composition (odds ratio 1.353; 95% confidence interval 1.003, 1.826). CONCLUSION: Red thrombi were present in nearly two-thirds of cases, and were associated with a longer ischaemic time and higher incidence of major adverse cardiovascular events in hospital.
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spelling pubmed-55367572017-10-03 Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes Yang, Yapan Li, Jingchao Xu, Wenke Dong, Shujuan Yu, Haijia Song, Huihui Chu, Yingjie J Int Med Res Clinical Reports OBJECTIVE: To investigate differences in clinical and angiographic outcomes between patients with acute myocardial infarction with red and white thrombi. METHODS: A total of 137 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary interventions were included. Thrombus material was classified as white or red based on its pathology. Information on characteristics of thrombi was available for 97 (70.8%) patients. RESULTS: The total ischaemic time was significantly longer in the red thrombus group compared with the white thrombus group. The incidence of major adverse cardiovascular events in hospital was higher in the red thrombus group than in the white thrombus group (15.6% vs 0%). Multivariable logistic analysis showed that the total ischaemic time was the only predictor of thrombus composition (odds ratio 1.353; 95% confidence interval 1.003, 1.826). CONCLUSION: Red thrombi were present in nearly two-thirds of cases, and were associated with a longer ischaemic time and higher incidence of major adverse cardiovascular events in hospital. SAGE Publications 2016-11-10 2016-12 /pmc/articles/PMC5536757/ /pubmed/27834302 http://dx.doi.org/10.1177/0300060516667373 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Reports
Yang, Yapan
Li, Jingchao
Xu, Wenke
Dong, Shujuan
Yu, Haijia
Song, Huihui
Chu, Yingjie
Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes
title Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes
title_full Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes
title_fullStr Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes
title_full_unstemmed Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes
title_short Thrombus aspirated from patients with ST-elevation myocardial infarction: Clinical and angiographic outcomes
title_sort thrombus aspirated from patients with st-elevation myocardial infarction: clinical and angiographic outcomes
topic Clinical Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536757/
https://www.ncbi.nlm.nih.gov/pubmed/27834302
http://dx.doi.org/10.1177/0300060516667373
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