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Highly sensitive protein detection by biospecific AFM‐based fishing with pulsed electrical stimulation
We report here the highly sensitive detection of protein in solution at concentrations from 10(–15) to 10(–18) m using the combination of atomic force microscopy (AFM) and mass spectrometry. Biospecific detection of biotinylated bovine serum albumin was carried out by fishing out the protein onto th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537060/ https://www.ncbi.nlm.nih.gov/pubmed/28781958 http://dx.doi.org/10.1002/2211-5463.12253 |