Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia

Hemophagocytic lymphohistiocytosis (HLH) is a rare inflammatory condition with tissue destruction due to abnormal immune activation. We present a series of 2 cases of cytomegalovirus-induced HLH in children during maintenance chemotherapy for acute lymphoblastic leukemia. These cases emphasize the i...

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Detalles Bibliográficos
Autores principales: Waddell, Benjamin, Belcher, Chris, Willey, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537164/
https://www.ncbi.nlm.nih.gov/pubmed/28791218
http://dx.doi.org/10.1016/j.idcr.2017.07.003
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author Waddell, Benjamin
Belcher, Chris
Willey, Emily
author_facet Waddell, Benjamin
Belcher, Chris
Willey, Emily
author_sort Waddell, Benjamin
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is a rare inflammatory condition with tissue destruction due to abnormal immune activation. We present a series of 2 cases of cytomegalovirus-induced HLH in children during maintenance chemotherapy for acute lymphoblastic leukemia. These cases emphasize the importance of considering secondary HLH in this high-risk subset of pediatric patients.
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spelling pubmed-55371642017-08-08 Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia Waddell, Benjamin Belcher, Chris Willey, Emily IDCases Case Report Hemophagocytic lymphohistiocytosis (HLH) is a rare inflammatory condition with tissue destruction due to abnormal immune activation. We present a series of 2 cases of cytomegalovirus-induced HLH in children during maintenance chemotherapy for acute lymphoblastic leukemia. These cases emphasize the importance of considering secondary HLH in this high-risk subset of pediatric patients. Elsevier 2017-07-22 /pmc/articles/PMC5537164/ /pubmed/28791218 http://dx.doi.org/10.1016/j.idcr.2017.07.003 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Waddell, Benjamin
Belcher, Chris
Willey, Emily
Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
title Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
title_full Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
title_fullStr Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
title_full_unstemmed Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
title_short Cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
title_sort cytomegalovirus induced hemophagocytic lymphocytic histiocytosis in two pediatric patients with acute lymphoblastic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537164/
https://www.ncbi.nlm.nih.gov/pubmed/28791218
http://dx.doi.org/10.1016/j.idcr.2017.07.003
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AT willeyemily cytomegalovirusinducedhemophagocyticlymphocytichistiocytosisintwopediatricpatientswithacutelymphoblasticleukemia

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