Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters

Infections of immunocompromised patients with human adenoviruses (hAd) can develop into life-threatening conditions, whereas drugs with anti-adenoviral efficiency are not clinically approved and have limited efficacy. Small double-stranded RNAs that induce RNAi represent a new class of promising ant...

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Detalles Bibliográficos
Autores principales: Schaar, Katrin, Geisler, Anja, Kraus, Milena, Pinkert, Sandra, Pryshliak, Markian, Spencer, Jacqueline F., Tollefson, Ann E., Ying, Baoling, Kurreck, Jens, Wold, William S., Klopfleisch, Robert, Toth, Karoly, Fechner, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537171/
https://www.ncbi.nlm.nih.gov/pubmed/28918031
http://dx.doi.org/10.1016/j.omtn.2017.07.002

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